Immune System Concept Map Template

The
Immune System
Part 4
IIIness
Stimulation/control of immune response
Parts 1 and 2
Immunity
Immunology
Mammalian immunologic
Development
"immunis" or exempt
Function of immune system is to protect from
invasion by infectious oraganisms, toxic agents,
and abonormal cells (cancer)
Cells and non-cellular components
Factors affecting immunity
3 arms
Host barriers
Natural immunity
Adaptive immunity
Comparison of Natural and
Adaptive Immunity
Antigens
Antibodies
Complement
Leukocytes
Lymphocytes
Cytokiness
System of circulating proteins
activated by antibody-antigen
reaction
Activated compliment system:
Functions
nomenclature
Pathways
White blood cells
Participate/regulate immune responses
Types:
Granulocytes (65%)
Monocytes (5%)
Lymphocytes (30%)
Neutrophils(98%)
Eosinophils (2%)
Basophils(0.5%)
Mononuclear-Macrophage system
Specialized immune cells
differentiate along the lymphoid pathways
Types:
Self Tolerance and Lymphocyte Maturation
Suppresses exacess spread of
inflammatory response
Can kill certain parasites through
oxidative mechanisms
increased in allaergies and parasitic infections
Granules are pink
Mast cells
Actu, System hypersensitivity
Granules contain
Ag binds to two adjacent IgE on
basophil slurface
Widely distributed throught
the body (fixed or wandering)
Macrophages/Monocytes
Homeostatic regulator of inflammation
Causes degranulation
Phagocytosis and antigen presentation
Increased vascular permeability
Smooth muscle spasm
Vasodilation
Anaphylactic shock
Part 3
Cell Injury
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