MindMap Gallery Diabetes Mellitus Mind Map
A mind map about Diabetes Mellitus.
Diabetes Mellitus
Type 2
pathophysiology
insulin resistance where cells don't respond to insulin properly
insufficient insulin production from beta cells
causes
- Gene mutations
- TCF 12; endcodes for secretion of insulin
- PPAR-y; adipocyte differentiation and glucosemetabolism
lifestyle
obesity
high carbohydrate intake
insufficient excersize
medications
betablockers
glucocorticoids
statins
antipsychotics
Diagnostic Test
fasting blood glucose
glucose tolerance test
treatment
insulin
oral hypoglycemics
lifestyle changes
gestational
pregnant women with no past history of diabetes
occurs in about 2 - 10% of pregnancies
resembles type 2
usually returns to normal after delivery
Type 1
Pathophysiology
Auto-antibiodies are formed againstpancreatic cells
T-cells infiltrate pancreas kill insulinproducing B cells
Genetic Risk factors
HLA 2 gene mutation
Aspartic acid on position 57 mutates andchanges shape of the molecule
Causitive Factors
Genetic factors not exclusively responsiblefor disorder, viral infections activateautoimmune response
oral hypoglycemics dont work
