Function

Function

The place where T and B lymphocytes live

site of immune response

filtering effect

Participates in lymphocyte recirculation (HEV)

Where T cells and B cells colonize

where the immune response occurs

filtering effect

Synthesis of biologically active substances (complements, cytokines)

Exerting mucosal local immune response

Produce secretory IgA (SIgA)

Lymphocytes designated to reside in peripheral immune organs enter the blood circulation from the efferent lymphatic vessels through the lymphatic trunk, thoracic duct or right lymphatic duct. After reaching the peripheral immune organs through the blood circulation, they pass through the HEV and are redistributed to lymphoid organs and tissues throughout the body. cycle process.

Makes the distribution of lymphocytes throughout the body more reasonable and contributes to the immune response of the entire body.

It increases the opportunity for lymphocytes to contact antigens, expands immune recognition, and is conducive to the generation of adaptive immune responses.

It makes the systemic immune organs and tissues into an organically connected whole and transmits immune information to immune cells throughout the body, which is conducive to mobilizing them to migrate to the location of pathogenic tumors or other antigenic foreign bodies to exert immune effects.