MindMap Gallery Endocrine Disorders and Tests
This is a mind map of Endocrine Disorders and Tests. You can make and share your own mind maps easily. Just try EdrawMind mind mapping software for free!
Edited at 2022-11-17 09:34:30This is a mind map of basic diagnostic test steps for bacteriology. Bacteriology is the branch and specialty of biology that studies the morphology, ecology, genetics, and biochemistry of bacteria as well as many other aspects related to them.
This is a mind map of basic diagnostic tests for bacteriology. Bacteriology is the branch and specialty of biology that studies the morphology, ecology, genetics, and biochemistry of bacteria as well as many other aspects related to them.
This is a mind map of Endocrine Disorders and Tests. You can make and share your own mind maps easily. Just try EdrawMind mind mapping software for free!
This is a mind map of basic diagnostic test steps for bacteriology. Bacteriology is the branch and specialty of biology that studies the morphology, ecology, genetics, and biochemistry of bacteria as well as many other aspects related to them.
This is a mind map of basic diagnostic tests for bacteriology. Bacteriology is the branch and specialty of biology that studies the morphology, ecology, genetics, and biochemistry of bacteria as well as many other aspects related to them.
This is a mind map of Endocrine Disorders and Tests. You can make and share your own mind maps easily. Just try EdrawMind mind mapping software for free!
ENDOCRINE DISORDERS & TESTS
HYPOSECRETION OF GROWTH HORMONE
ACROMEGALY
SCREENING
randomly collectedIGF-I
if elevated = confirmatory is needed
CONFIRMATORY
OGTT (75 g)
glucose & gh:- collected every30 mins for the next2 hours
fails to drop gh (<1ng/mL)= ACROMEGALY
GH HYPERSECRETIONTHERAPY
normalizes IGF-I
suppresses GH responseto OGTT to < 1 ng/mL
HYPERSECRETION OF GROWTH HORMONE
GROWTH HORMONE DEFICIENCY
SCREENING
exercise / physicalactivity test
stress = increasesGH
fails to increase= confirmatory
CONFIRMATORY
GOLD STANDARD
INSULINTOLERANCE TEST
expected:adult = < 5children = <10
cannot be performedto px w/ seizure, cardiac/cerebrovascular ds
2ND confirmatorytest is required
2ND
ARGININETOLERANCE TEST
expected:adult = < 5children = <10
OTHER TESTS
24HR / NIGHTTIME MONITORINGOF GH
HYPOSECRETION OF ANTIDIURETIC HORMONE
DIABETES INSIPIDUS(TYPE 2)
WATER DEPREVATION TEST
px deprived of water = 8-12 hours
urine & plasma osmolality are taken
administration ofexogenous AVPor desmopressin
urine & plasma osmolality are checkedagain
NEUROGENIC
defect on the glandthat produces ADH
decreased ADH
NEPHROGENIC
defect on the ADH receptor of kidneys
unresponsive= normal levels
HYPERCORTICOLISM
CUSHING'S SYNDROME
SCREENING
24HR URINARYCORTISOL
upper range:= 110-138 nmol/24hr
cushing's = > 4x
OVERNIGHT DEXAMETHASONESUPPRESSION TEST
1mg dexa (orally)= bet 11pm and 12 mid
plasma cortisol drawnthe ff morning= 8am and 9am
cushing's = <1.8 g/dL
LATE-NIGHT (11PM)SALIVARY CORTISOL
chew on cotton pledget for 2-3 mins
drool directlyon test tube
expected: decreased level of cortisol
CONFIRMATORY
MIDNIGHT PLASMACORTISOL
48hr hospital admission
IV access: before 10 pm
blood draw: px asleep
cushing's = >7.5g/dL
LOW-DOSE DEXASUPPRESSION TEST
two baseline 24 hr urine
orally: 0.5 mg dexamethasoneevery 6 hours. start at 9am for 2 days
normal = decreased urinecortisol to <10 ug/24hrs on 2nd day of dex
HYPERALDOSTERONISM
PRIMARY ALDOSTERONISM
SCREENING
PLASMA ALDOSTERONECONCENTRATION/PLASMARENIN ACTIVITY (PAC/PRA) RATIO
px: remain upright for atleast 2hrs
primary aldo = > 30
CONFIRMATORY
SALINE SUPPRESSION
2L 0.9% salineover 4 hrs
10-12g dailyfor 3 days
PAC is measured at the end of 4-hr
primary aldo = >10ng/dL
CAPTOPRIL SUPPRESSION
w/n 3hrs of taking 50mg captopril
plasma aldosterone= remains high
ADRENAL INSUFFICIENCY
HYPOCORTICOLISM
SCREENING
BASAL HORMONEMEASUREMENTS
8am-9am plasma cortisol= <3 ug/dL
ACTH STIMULATIONTEST
baseline serum cortisolis measured
administer 250ug COSYNTROPIN
after 30 and 60 mins- serum cortisol is collected again
normal = >18-20ug/dL
adrenal insu = lower levelsare consistent
CONFIRMATORY
OVERNIGHTMETYRAPONETEST
orally at midnight: metyraprone = 30mg/kg
collect @ 8am- blood for cortisol& 11-deoxycortisol
normal:>7 g/dL 11-deoxy
PHEOCHROMOCYTOMA
SCREENING
24HR URINECATECHOLAMINES
VMA and HVA
CONFIRMATORY
PLASMA METANEPRHINEOR NORMETANEPHRINE
normeta:above 400ng/L
meta:above 236ng/L
PHARMACOLOGICTESTS
CLONIDINE SUPPRE
normal:norepi dec 50%
pheochro:norepi fail to dec
GLUCAGON STIMU
pheochro:threefold or greater inc in plasma NE = >2000pg/mL
HYPERGLYCEMIA
PRIMARY HYPOTHYROIDISM
PRIMARY HYPERTHYROIDISM
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