Digestive Tract

Ocular Effects

Skeletal Muscle

Ganglionic stimulation, hypotension, bradycardia, arrhythmia

Contraction of bladder, bronchoconstriction

Contraindicated for impaction with obstruction, pregnancy

Pupil constriction, dyspnea, bradycardia, hypotension

Respiratory paralysis + increased bronchiolar secretion (death)

Neostigmine: skeletal muscle weakness, nausea, vomiting, colic, diarrhea

Physostigmine: stimulation followed by CNS depression, convulsions

Treatment: Atropine