This ANS drugs concept map nursing depicts autonomic drugs that can inhibit or enhance the parasympathetic and sympathetic nervous systems' functions. This type of medication can treat various conditions, including glaucoma, asthma, urinary, gastrointestinal, and cardiopulmonary disorders. Activating the parasympathetic nervous system can result in significant physiological effects such as an increase in the glandular secretion, an increase in smooth muscle contraction, and a decrease in both heart contractility and heart rate. Neurotransmission involves two types of nicotinic receptors and muscarinic receptors to achieve the aforementioned physiological effects. These two receptor groups can bind to the same neurotransmitter, acetylcholine, to relay neurotransmission in the synapse.
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ACHReceotors
Muscarinic
Agonists
Pilocarp ine(used to treat glaucoma via M3)
Met hacho line(diagnose asthma, causes bronchoconstr iction)
Bethanecol(b ladder contraction, trats urinary retention via M3)
Su xametho nium(depolar ising blocker - muscle relax ant .Is a partial agonist- prevents furtherdepoler is ation so has antagon is tic effects)
Antagonists
Botulinum(prevents presynaptic ACh ree ase)
Tubocurar in e analo gues: mivacur iu m, atracurium, vecuro nium , pancuro nium (blocks ACh binding- muscle relaxanf)
ACHEInhibitors
Short-acting 4 alcohol
Edrophonium- diagnoses MG- revers be binding to anionic site
Medium- acting carbamyl ester
Neosting mine - MGPhysostigmine- MG, alzheimers, delayed gastric e mpty ing
Irreversible block
Echothiopate & dyflos eye drops for glaucoma (pe ntavalent p hosp horus compounds)(reversed by pralidoxime+M antgonist (at rop ine) in first 1-2 hours)
Non-specific
Agonists
adrena line(increases HR, constrcts blood vessels, diates air pas sages.actions vary by tissue type and expression of adrenergic rece ptors.
B1=B2
Agonists
Iso prenaline(treats bradyc ardia , astham. contra-indicated for my ocardial ischemia)
Antagonists
Propranolol(treats tachycardia)
B2
Agonists
Terbutaline & Salbutamol(bronchodlators. Saibutamol also used to today labour)
B1
Agonists
Dobutamine(treats heart failure and c ardio shock)
Antagonists
Metopro lol & Ate nolol(treat cardiseas es)
a2
Agonists
Clonid ine(treats high BP)
a1
Agonists
Phenylephrine(deco nges tant, inc reases BP)
Antagonists
Prazosin (treats high bbod pressure , anxiety, PTSD
Sympathomimetcs = adrenergc agonistssympathomimetcs=adrenergc a nta gonists
a receptors are in blood v essels, cause contraction, the refore increas e BP
B1 rec eptors are in heart: increase HR, COB2 rec eptors cause smooth muscle re laxation (bladder, bronchi, uterus)
Sympathomimetcs = adrenergc agonistssympathomimetcs=adrenergc a nta gonists
a receptors are in blood v essels, cause contraction, the refore increas e BP
B1 rec eptors are in heart: increase HR, COB2 rec eptors cause smooth muscle re laxation (bladder, bronchi, uterus)
Muscarinic AChR found in receptorsof Parasympathic Innervatiion(exception - MACHR in Sweatglands are sympathetic
M1 - neural & GI motility - excitationM2 - Cardiac Inhbtion - InhibitionM3 - glandular secretions andvasodlation via No - excitation
Nicotonic AChR foundin Skeletal muscle andall postgang fonicneurone in ANS
AChE Inhibitors are indirectchollnergic agonists - theyincrease the effects of AChat the re Ceptor. Mainly Meffects seen at low does.Toxic gases usesd in Syriaand as linse cticides
ANS Drugs Concept Map Nursing
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EdrawMind
ACH
Receotors
ACHE
Inhibitors
Non-specific
B1=B2
B2
a1
Agonists
Antagonists
Prazosin
(treats high bbod pressure , anxiety, PTSD
Phenylephrine
(deco nges tant, inc reases BP)
B1
a2
Agonists
Clonid ine
(treats high BP)
Agonists
Agonists
Antagonists
Metopro lol & Ate nolol
(treat cardiseas es)
Dobutamine
(treats heart failure and c ardio shock)
Agonists
Terbutaline & Salbutamol
(bronchodlators. Saibutamol also used to today labour)
Agonists
Antagonists
Propranolol
(treats tachycardia)
Iso prenaline
(treats bradyc ardia , astham. contra-indicated for my ocardial ischemia)
adrena line
(increases HR, constrcts blood vessels, diates air pas sages.
actions vary by tissue type and expression of adrenergic rece ptors.
Sympathomimetcs = adrenergc agonists
sympathomimetcs=adrenergc a nta gonists
a receptors are in blood v essels, cause contraction, the refore increas e BP
B1 rec eptors are in heart: increase HR, CO
B2 rec eptors cause smooth muscle re laxation (bladder, bronchi, uterus)
Short-acting 4 alcohol
Medium- acting carbamyl ester
Irreversible block
Echothiopate & dyflos eye drops for glaucoma (pe ntavalent p hosp horus compounds)
(reversed by pralidoxime+M antgonist (at rop ine) in first 1-2 hours)
Neosting mine - MG
Physostigmine- MG, alzheimers, delayed gastric e mpty ing
Edrophonium- diagnoses MG- revers be binding to anionic site
Muscarinic
Nicotonic
Agonists
Antagonists
Agonists
Antagonists
Pilocarp ine
(used to treat glaucoma via M3)
Met hacho line
(diagnose asthma, causes bronchoconstr iction)
Bethanecol
(b ladder contraction, trats urinary retention via M3)
Su xametho nium(depolar ising blocker - muscle relax ant .Is a partial agonist- prevents furtherdepoler is ation so has antagon is tic effects)
Antagonists
Botulinum(prevents presynaptic ACh ree ase)
Tubocurar in e analo gues: mivacur iu m, atracurium, vecuro nium , pancuro nium (blocks ACh binding- muscle relaxanf)
ACHEInhibitors
Short-acting 4 alcohol
Edrophonium- diagnoses MG- revers be binding to anionic site
Medium- acting carbamyl ester
Neosting mine - MGPhysostigmine- MG, alzheimers, delayed gastric e mpty ing
Irreversible block
Echothiopate & dyflos eye drops for glaucoma (pe ntavalent p hosp horus compounds)(reversed by pralidoxime+M antgonist (at rop ine) in first 1-2 hours)
Non-specific
Agonists
adrena line(increases HR, constrcts blood vessels, diates air pas sages.actions vary by tissue type and expression of adrenergic rece ptors.
B1=B2
Agonists
Iso prenaline(treats bradyc ardia , astham. contra-indicated for my ocardial ischemia)
Antagonists
Propranolol(treats tachycardia)
B2
Agonists
Terbutaline & Salbutamol(bronchodlators. Saibutamol also used to today labour)
B1
Agonists
Dobutamine(treats heart failure and c ardio shock)
Antagonists
Metopro lol & Ate nolol(treat cardiseas es)
a2
Agonists
Clonid ine(treats high BP)
a1
Agonists
Phenylephrine(deco nges tant, inc reases BP)
Antagonists
Prazosin (treats high bbod pressure , anxiety, PTSD
Sympathomimetcs = adrenergc agonistssympathomimetcs=adrenergc a nta gonists
a receptors are in blood v essels, cause contraction, the refore increas e BP
B1 rec eptors are in heart: increase HR, COB2 rec eptors cause smooth muscle re laxation (bladder, bronchi, uterus)
Sympathomimetcs = adrenergc agonistssympathomimetcs=adrenergc a nta gonists
a receptors are in blood v essels, cause contraction, the refore increas e BP
B1 rec eptors are in heart: increase HR, COB2 rec eptors cause smooth muscle re laxation (bladder, bronchi, uterus)
Muscarinic AChR found in receptorsof Parasympathic Innervatiion(exception - MACHR in Sweatglands are sympathetic
M1 - neural & GI motility - excitationM2 - Cardiac Inhbtion - InhibitionM3 - glandular secretions andvasodlation via No - excitation
Nicotonic AChR foundin Skeletal muscle andall postgang fonicneurone in ANS
AChE Inhibitors are indirectchollnergic agonists - theyincrease the effects of AChat the re Ceptor. Mainly Meffects seen at low does.Toxic gases usesd in Syriaand as linse cticides
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