ANS Drugs Concept Map Nursing

EdrawMind
ACH
Receotors
ACHE
Inhibitors
Non-specific
B1=B2
B2
a1
Agonists
Antagonists
Prazosin
(treats high bbod pressure , anxiety, PTSD
Phenylephrine
(deco nges tant, inc reases BP)
B1
a2
Agonists
Clonid ine
(treats high BP)
Agonists
Agonists
Antagonists
Metopro lol & Ate nolol
(treat cardiseas es)
Dobutamine
(treats heart failure and c ardio shock)
Agonists
Terbutaline & Salbutamol
(bronchodlators. Saibutamol also used to today labour)
Agonists
Antagonists
Propranolol
(treats tachycardia)
Iso prenaline
(treats bradyc ardia , astham. contra-indicated for my ocardial ischemia)
adrena line
(increases HR, constrcts blood vessels, diates air pas sages.
actions vary by tissue type and expression of adrenergic rece ptors.
Sympathomimetcs = adrenergc agonists
sympathomimetcs=adrenergc a nta gonists
a receptors are in blood v essels, cause contraction, the refore increas e BP
B1 rec eptors are in heart: increase HR, CO
B2 rec eptors cause smooth muscle re laxation (bladder, bronchi, uterus)
Short-acting 4 alcohol
Medium- acting carbamyl ester
Irreversible block
Echothiopate & dyflos eye drops for glaucoma (pe ntavalent p hosp horus compounds)
(reversed by pralidoxime+M antgonist (at rop ine) in first 1-2 hours)
Neosting mine - MG
Physostigmine- MG, alzheimers, delayed gastric e mpty ing
Edrophonium- diagnoses MG- revers be binding to anionic site
Muscarinic
Nicotonic
Agonists
Antagonists
Agonists
Antagonists
Pilocarp ine
(used to treat glaucoma via M3)
Met hacho line
(diagnose asthma, causes bronchoconstr iction)
Bethanecol
(b ladder contraction, trats urinary retention via M3)
Atropine (treats muschroom poisoning , prevents bronchoconstr iction)
Hyoscine (anti- emetic . Motons ickness)
piren zepine (M1 , inhibits gastric acid sec retion - trests uicers)
Benztro pine ( anti - parkinson ian dyskinesia)
Ipratropium (bronchodillation - treats as thma)
Carbach ol (treat glaucome)
Su xametho nium
(depolar ising blocker - muscle relax ant .
Is a partial agonist- prevents further
depoler is ation so has antagon is tic effects)
Botulinum
(prevents presynaptic ACh ree ase)
Tubocurar in e analo gues: mivacur iu m, atracurium, vecuro nium , pancuro nium
(blocks ACh binding- muscle relaxanf)
Sympathomimetcs = adrenergc agonists
sympathomimetcs=adrenergc a nta gonists
a receptors are in blood v essels, cause contraction, the refore increas e BP
B1 rec eptors are in heart: increase HR, CO
B2 rec eptors cause smooth muscle re laxation (bladder, bronchi, uterus)
Muscarinic Excess->
DUMBELS
Defecation
Urination
Mosis (Puplis contract)
Bronchoconstriction
Emesis
Lacrimation
Salvation
Muscarinic AChR found in receptors
of Parasympathic Innervatiion
(exception - MACHR in Sweat
glands are sympathetic
M1 - neural & GI motility - excitation
M2 - Cardiac Inhbtion - Inhibition
M3 - glandular secretions and
vasodlation via No - excitation
Nicotonic AChR found
in Skeletal muscle and
all postgang fonic
neurone in ANS
AChE Inhibitors are indirect
chollnergic agonists - they
increase the effects of ACh
at the re Ceptor. Mainly M
effects seen at low does.
Toxic gases usesd in Syria
and as linse cticides
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