Body temperature exceeds 38 degrees Celsius

Feeling of severe chills

Lymph nodes in the groin, armpits, or neck are particularly noticeable

Enlarged lymph nodes with significant tenderness

Pathological rash or petechiae appear purple-black

Skin lesions may include gangrene and ulcers

Recent exposure to plague-infected rodents

May be spread through insect vectors such as fleas

Live in an area where plague is prevalent

Have recently traveled to areas where plague is prevalent

Apply antibodies to react with pathogens

Determine whether you are infected with plague by observing whether a fluorescent signal occurs

Extraction of pathogen DNA from clinical specimens

Amplification of pathogen DNA by PCR to identify plague infection

Take a chest X-ray

Watch the lungs for nodules or other abnormalities

Get a CT scan of your chest or abdomen

Produce detailed imaging images to aid diagnosis of plague

Extraction of plague pathogens from clinical specimens

Purification of pathogens by culture and isolation methods

Detection of plague-specific markers using specific antibodies or proteins

Determining plague infection by detecting specific markers