Plague is an infectious disease caused by Yersinia pestis

Yersinia pestis is mainly spread by fleas

Plague occurs all over the world

Morbidity and mortality are related to geographic factors

Flea bites are the most common form of infection

There are two main types of plague: plague tumor and plague pneumonia.

Early symptoms of plague include fever, headache and fatigue

The course of the disease can progress to serious consequences such as bubonic plague, septicemia, and pneumonic plague.

Culture and identification of Yersinia pestis

Molecular diagnostic methods such as PCR and real-time fluorescence PCR

Antibody testing and serology testing

Establishment and maintenance of local and global monitoring networks

Observe the patient’s disease history and symptoms

Check lymph nodes and tissue samples, etc.

Imaging technologies such as X-rays and CT scans

Observe plague-related lesions and lesions

Monitor the number of infections and regional distribution

Analyze the spatiotemporal spread of the epidemic

Investigate alternative sources of infection for cases

Tracing and isolating possible cases and infected persons

Molecular epidemiological research using genetic sequencing and typing technologies

Determining the virulence and transmission routes of Yersinia pestis

Using big data and artificial intelligence technology for epidemic prediction

Early warning and response to plague outbreaks