MindMap Gallery Blood mind map
This is a mind map about blood, including its components, physical and chemical properties, blood types, etc.
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This is a mind map about bacteria, and its main contents include: overview, morphology, types, structure, reproduction, distribution, application, and expansion. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about plant asexual reproduction, and its main contents include: concept, spore reproduction, vegetative reproduction, tissue culture, and buds. The summary is comprehensive and meticulous, suitable as review materials.
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blood
component
plasma
Definition: An aqueous solution containing multiple solutes
Include
Water (90%-92%)
solute
plasma proteins
It is a general term for various proteins in plasma
Salting out method → albumin, globulin, fibrin
Albumin/globulin (A/G) = (1.5-2.5): 1
Albumin and most globulin are produced by the liver → Whether the liver function is normal? When liver dysfunction occurs, the A/G ratio decreases, or even the ratio is inverted (cirrhosis)
Function
Is a general term for multiple proteins in plasma
Maintain the relative concentrations of thyroid hormones, adrenocortical hormones, and sex hormones in plasma
As a carrier to transport low molecular substances - lipids, ions, vitamins, metabolic wastes, drugs
Participate in physiological processes such as blood coagulation, anticoagulation, and fibrinolysis
nutritional function
crystalline matter
Inorganic salt: electrolyte (Na⁺, Cl⁻, K⁺, etc.): about 300mmo
Protein nitrogen-containing organic matter: amino acids (3.2-5.9mmol/L), urea (3.2-7.1mmol/L)
Non-protein nitrogen-free organic matter: glucose (3.9-6.1mmol/L)
blood cells
Classification
Red blood cells (most numerous)
generate
Ingredients: Protein➕Iron Iron deficiency
Maturation factors: folic acid, VitB
Regulation: EPO, sex hormone
destroy
spleen
characteristic
Suspension stability: the most important property required for red blood cell survival
Osmotic fragility: the characteristic of red blood cells that swell and rupture in hypotonic saline solutions
Plasticity: the most important property required for red blood cell survival
Function: Transport O₂ and CO₂
Normal value: Adult male (4.0-5.5) × 10¹²/L Adult female (3.5-5.0) 10¹²/L
White blood cells (minimum number)
Normal value: (4.0-10.0)×10⁹/L
Classification
Neutrophils: engulf bacteria and necrotic cells
Basophils: ① Limit allergic reactions caused by mast cells and basophils ② Participate in the immune response to worms
Eosinophils: release histones, anaphylaxis, heparin, and eotaxin A
Monocytes: ①phagocytosis of pathogenic microorganisms ②Senescent cells ③Participate in specific immunity
Lymphocytes: ①T lymphocytes, B lymphocytes and natural killer cells ②T lymphocytes mainly participate in cellular immunity ③B lymphocytes mainly participate in humoral immunity
platelets
Normal value: (100-300)×10⁹/L
Function: ① Participate in physiological hemostasis ②Promote blood coagulation ③Maintain the integrity of blood vessel walls
Hematocrit
Definition: The volume percentage of blood cells in whole blood
Proportion
Adult males (40%-50%)
Adult women (37%-48%)
It can reflect the relative concentration of red blood cells in the blood (hematocrit in patients with anemia ↓ and hematocrit in patients with diarrhea and burns ↑)
Physical and chemical properties
blood color
The red blood cells in the arteries contain more oxygen and hemoglobin and are bright red.
The red blood cells in the veins contain a lot of deoxygenated hemoglobin and are dark red.
specific gravity of blood
The specific gravity of normal human whole blood is 1.050-1.060. The greater the number of red blood cells, the greater the specific gravity of whole blood.
Plasma specific gravity 1.025-1.030 → positively correlated with the amount of plasma proteins
The specific gravity of red blood cells is 1.090-1.092 → positively correlated with the hemoglobin content
blood viscosity
Whole blood viscosity: depends on hematocrit
Plasma viscosity: depends on plasma protein content
plasma pH
buffer substance
NaHCO₃/HCO₃ (20:1)
protein sodium salt/protein
NaHPO₄/NaH₂PO₄
buffer system
Body fluid buffering - buffering regulation (HCO₃⁻/H₂CO₃)
Lungs – Expelling CO₂ through lung ventilation
Tissue cells - ion exchanger and intracellular fluid buffer pair
Kidney - renal tubular epithelial cells secrete hydrogen and retain alkali
Osmotic pressure (7.35-7.45)
Refers to the ability of all solutions to attract and retain water molecules
High or low → the number of solute particles (molecules or ions) in the solution
include
plasma crystalloid osmotic pressure
composition
Osmotic pressure formed by small molecular substances (NaCl, glucose, urea) in plasma. 80% of which is NaCl
Function
Physiological significance: maintain water balance inside and outside cells and maintain normal cell morphology
Pathological significance: Sodium pump dysfunction leads to cellular edema (increased intracellular fluid)
example
Hypertonic solution - 20% glucose → hangover relief (relief)
isotonic solution
0.85%/0.9% saline
5% glucose solution
hypotonic solution
Cause cell rupture → hemolysis
plasma colloid osmotic pressure
composition
Osmotic pressure formed by colloidal substances in plasma
Function
Physiological significance: maintain water balance inside and outside blood vessels and maintain blood volume
Pathological significance: hypoalbuminemia causes edema (increased tissue fluid)
Formed mainly from albumin
example
Liver, kidney disease or malnutrition → Plasma protein ↓ → Plasma colloid osmotic pressure ↓ → Transfer of water molecules to tissue fluid → Edema
blood type
ABO blood group system
Classification basis: There are four blood types based on the presence and type of antigens on the red blood cell membrane.
Type A: Antigen A on red blood cells and antibody B in plasma
Type B: Antigen B on red blood cells and antibody A in plasma
Type AB: Contains antigen A and antigen B on red blood cells and no related antibodies in the plasma
Type O: no relevant antigen on red blood cells, antibody A and antibody B in plasma
RH blood group system
Classification: if there is D antigen on the red blood cell membrane, it is RH positive; if there is no D antigen, it is RH negative.
Features: There are no natural antibodies against RH in serum.
Principle of blood transfusion: Adhere to blood transfusion of the same type and perform cross-matching experiments