MindMap Gallery Composition, physical and chemical properties and functions of blood
The composition, physical and chemical properties, and functional knowledge of blood are sorted out, and essential review materials are shared to make it easier for everyone to read and review when preparing for the exam, and to improve review efficiency. I hope it will be helpful to everyone preparing for the exam.
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This is a mind map about bacteria, and its main contents include: overview, morphology, types, structure, reproduction, distribution, application, and expansion. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about plant asexual reproduction, and its main contents include: concept, spore reproduction, vegetative reproduction, tissue culture, and buds. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about the reproductive development of animals, and its main contents include: insects, frogs, birds, sexual reproduction, and asexual reproduction. The summary is comprehensive and meticulous, suitable as review materials.
Composition, physical and chemical properties and functions of blood
Physiological function
transportation
buffer
defense and protection
Composition and physical and chemical properties
HP (blood volume)
Total amount of blood in the body
circulating blood volume
Rapid circulation in the cardiovascular system
Store blood volume
In the liver, lungs, celiac veins, and subcutaneous venous plexus, the flow is very slow
There are 70 to 80ml of blood per kilogram of body weight
composition
plasma (plasma)
protein
Albumin/Albumins
globulins
Fibrinogen
water
other
electrolyte
small organic molecules
gas
blood cells
erythrocyte/RBC
leukocyte /WBC
Neutrophils Neutrophils
Lymphocytes Lymphocytes
Monocytes
Eosinophils Eosinophils
Basophils
platelets
Hematocrit (hematocrit)
Percentage of volume occupied by blood cells in blood
Reference
adult male
40%~50%
adult women
37%~48%
newborn
about 55%
significance
Reflects the relative concentration of red blood cells in the blood (WBC and PLT occupy a very small amount in the blood)
Physical and chemical properties
#️⃣Proportion
Whole blood 1.050~1.060
Red blood cells 1.090~1.092
Plasma 1.025~1.030
viscosity (viscosity)
Reference
Whole blood 4~5
Depends on HCT
Plasma 1.6~2.4
Depends on plasma protein content
RBC↑ → HCT↑ →Viscosity↑→Blood flow resistance↑
plasma osmolarity (blood osmotic pressure)
The attraction of solute molecules in a solution to water through a semipermeable membrane
Positively related to the number of solute particles
Independent of solute type and particle size
normal value
300mmol/L
composition
plasma crystalloid osmotic pressure
Maintain water balance inside and outside the cell membrane
plasma colloid osmotic pressure
Maintain water balance inside and outside blood vessels
Crystalloid osmotic pressure > Colloidal osmotic pressure
plasma pH
normal value
7.35~7.45
<7.35: acidosis
>7.45: alkalosis
buffer system
The most important: NaHCO3/H2CO3
Blood cell morphology and physiology
RBC
form and quantity
normal value
Male: (4.5~5.4) x 10^12/L
Female: (3.8~4.6) x 10^12/L
Newborn: >6x10^12/L
diameter
7.5~8.5um
Biconcave disc shape
Hemoglobin
normal value
Male: 120~160g/L
Female: 110~150g/L
Newborn: >200g/L
anemia
The number of RBCs and Hb concentration in the blood are lower than normal HCT↓
Polycythemia
RBC number and Hb concentration are higher than normal HCT ↑
Physiological properties
permeability
Large molecules cannot pass, but O2 and CO2 can pass
When blood is stored at low temperature for a long time, the concentration of K in the plasma increases.
Reason: Metabolism almost stops at low temperature and the Na-K pump is inactivated
Plastic deformability (plastic deformation)
Normal RBCs have the ability to deform under the action of external forces
The most important characteristics RBC needs for survival
Influencing factors
RBC geometry
RBC internal viscosity
The greater the viscosity, the smaller the deformation ability
Hb
Red blood cell membrane elasticity
suspension stability (suspension stability)
RBCs have the property of remaining dispersed and suspended in plasma without sinking easily.
Erythrocyte sedimentation rate (ESR/ erythrocyte sedimentation rate)
Express the RBC sinking velocity as the distance the RBC sinks at the end of the first hour
normal value
Male: 0~15mm/h
Female: 0~20mm/h
Influencing factors
Fibrinogen, globulin, cholesterol in plasma ↑, RBC concatenation and ESR ↑
Albumin and lecithin in plasma ↑, inhibit concatenation, ESR ↓
Osmotic fragility (osmotic fragility)
Characteristics of RBC swelling and rupture in hypotonic saline solution
Osmotic fragility is high, and the cell membrane has little resistance to hypotonic salt solutions and is easily ruptured.
Under physiological conditions, aging RBCs are more fragile and newly mature RBCs are less fragile.
When the NaCl concentration drops to 0.42%, some RBCs begin to rupture and hemolysis occurs.
WBC
PLT
form
biconvex disc shape
Diameter 2~3um
No nucleus
normal value
Adult: (100~300)x 10^9/L
>400 x 10^9/L
<100x 10^9/ L
Function
Participate in physiological hemostasis
Promote blood clotting
Maintain blood vessel wall integrity
Physiological properties
stick
gather
freed
shrink
Adsorption
Red blood cells of patients with hereditary spherocytosis
Plastic deformability↓
Suspension stability↓
Osmotic brittleness↑