MindMap Gallery blood
Blood is a red, opaque, viscous liquid that flows in the human blood vessels and heart. Blood is composed of plasma and blood cells. One liter of plasma contains 900-910 grams of water, 65-85 grams of protein and 20 grams of low molecular substances. There are a variety of electrolytes and organic compounds in low molecular substances. Blood cells include red blood cells and white blood cells. and platelet cells. The average lifespan of red blood cells...
Edited at 2022-11-14 19:44:16This is a mind map about bacteria, and its main contents include: overview, morphology, types, structure, reproduction, distribution, application, and expansion. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about plant asexual reproduction, and its main contents include: concept, spore reproduction, vegetative reproduction, tissue culture, and buds. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about the reproductive development of animals, and its main contents include: insects, frogs, birds, sexual reproduction, and asexual reproduction. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about bacteria, and its main contents include: overview, morphology, types, structure, reproduction, distribution, application, and expansion. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about plant asexual reproduction, and its main contents include: concept, spore reproduction, vegetative reproduction, tissue culture, and buds. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about the reproductive development of animals, and its main contents include: insects, frogs, birds, sexual reproduction, and asexual reproduction. The summary is comprehensive and meticulous, suitable as review materials.
blood (Healthy adults 5L 7%)
composition
blood cells 45%
composition
red blood cells
leukocyte
platelets
plasma 55%
Function
Carry blood cells, nutrients and metabolites...
composition
Water (90%), plasma proteins, enzymes, lipoproteins, vitamins, inorganic salts, nutrients, metabolites
Without anticoagulant, blood rests outside the body Fibrinogen → fibrin (via thrombin) Serum: light yellow transparent liquid lacking fibrinogen in plasma Blood smear: Wright's stain (base: methylene blue acid: eosin) Hemogram: Measurement results of blood cell morphology, number ratio and hemoglobin in blood
Development of bone marrow and blood cells
Embryonic Development 3 Primitive blood cells occur in blood islands in the wall of the yolk sac 6 liver 12 spleen In the late embryonic stage, the bone marrow becomes the main site of hematopoiesis, and the thymus and lymph nodes are the sites of lymphocyte proliferation and differentiation.
bone marrow structure
red bone marrow
hematopoietic tissue
Reticular tissue and stromal cells constitute hematopoiesis-inducing microenvironment to regulate hematopoietic cells and hematopoiesis Reticular tissue is also a scaffold for hematopoietic tissue Stromal cells: macrophages, fibroblasts, sinusoidal endothelial, reticular, adipogenic, osteogenic, bone marrow stromal stem cells
Sinusoids
High permeability, which facilitates the entry of mature blood cells into the blood
yellow bone marrow
Adipose tissue
immature blood cells
Hematopoietic stem cells (pluripotent stem cells)
Self-replication, proliferation potential, multi-directional differentiation ability
Hematopoietic progenitor cells (directed)
Pluripotent stem cells → directed → primitive → naive (early, middle and late) → mature
red blood cells Male 4.0~5.5×10 to the twelfth power Female 3.5~5.0......
Blood type A B AB O RH negative panda blood Hh negative dinosaur blood
Morphology
Biconcave disc shape (facilitates rapid exchange of gases inside and outside the cell) Mature cells have no nuclei or organelles and are filled with hemoglobin.
hemoglobin Male 120~160g/L Female 110~150g/L Anemia: red blood cells less than 3×1012/L Hemoglobin less than 100g/L
Red blood cell membrane skeleton: mainly contains spectrin and actin. Make red blood cells flexible and elastic
Function
Transport oxygen and carbon dioxide
Aged red blood cells are phagocytized and cleared by macrophages in the spleen and liver. Average lifespan is 120 days Reticulocytes: immature, with bright tar blue staining, it can be seen that there are still blue-dyed fine meshes and particles (ribosomes) in the cytoplasm.
leukocyte (4~10x109th power/L)
Morphology
Colorless nucleated spherical cells
Function
Metamorphosis Movement Involved in defense and immune functions
Classification
granulocyte
neutrophils 50~70%
Morphology
The diameter is 10 to 12 microns, and the nucleus is rod-shaped or lobed. The lobed nucleus can be divided into 2 to 5 lobes, and there are chromatin threads connecting the lobes (the increase of the rod-shaped nucleus and the sum of 2 lobes is called left shift of the nucleus. The increase in nuclei in the 4th and 5th lobes is called nuclear right shift) Live in tissue for 2 to 3 days
Contains a large number of fine, evenly distributed particles dyed lavender and light red.
special particles
Small in size and light red in color. Accounting for 80%, it is a secreted granule containing lysophage and phagocytosin, which can kill bacteria.
azurophilic granules
Larger, lavender particles. 80%, is a lysosome
Function
Deformation movement, phagocytosis and secretion activities.
clinical significance
When acute inflammation occurs due to bacterial infection, the proportion of neutrophils increases significantly.
eosinophils 0.5~3%
Morphology
It is 10 to 15 microns in diameter and has a 2-lobed core. The polycytoplasm is filled with thick, evenly distributed, orange-red stained eosinophilic granules (special lysosomes, containing cationic proteins, aryl sulfatase, and histamine enzymes). Contains rectangular dense crystals
Function
Metamorphosis, chemotaxis, phagocytosis
clinical significance
Anti-allergic, anti-parasitic.
basophils 0~1%
Morphology
The smallest number and spherical shape. The diameter is 10 to 12 microns, and the core is lobed or S-shaped. The cytoplasm contains blue-purple basophilic granules of varying sizes and unevenly distributed, and the granules are long and covered on the membrane.
Function
Basophils and mast cells secrete the same substances and have basically the same functions, and are involved in allergic reactions.
agranulocytosis
monocytes 3~8%
Morphology
The largest cell among white blood cells, 14 to 20 microns in diameter and spherical in shape. The nucleus is kidney-shaped, horseshoe-shaped or irregular. The cytoplasm is rich in gray-blue color and contains many small lilac azurophilic granules.
Function
Deformation movement, chemotaxis, strong phagocytosis function, and can differentiate into macrophages.
Lymphocytes 20~30%
Morphology
The nucleus is round or oval, with a small depression on the inside. Divided into large, medium and small, the peripheral blood is mainly small, and large and medium has azurophilia. The cytoplasm is basophilically stained azure.
platelets 100~300×10 to the ninth power/L
Small pieces of cytoplasm shed by bone marrow megakaryocytes, biconvex disc-shaped, 2 to 4 microns in diameter Often gather in groups, life span is 7 to 14 days No nucleus, with organelles There are blue-purple platelet granules (granule area) in the center - containing special granules, dense granules and a small amount of lysosomes (hemostasis and coagulation) Peripheral light blue (transparent area)—contains microtubules and microfilaments, involved in the maintenance and deformation of platelet morphology