Skin purpura: Skin purpura occurs repeatedly, mostly on the limbs and buttocks, with symmetrical distribution and more extension sides. Purple-red maculopapular rash initially appears, does not fade after being suppressed - dark red - tan subsides (generally subsides in 4-6 weeks)

Gastrointestinal symptoms: paroxysmal severe abdominal pain, often located around the umbilicus and lower abdomen

Joint symptoms: swelling and pain in large joints such as knees, ankles, wrists, and elbows, and limited movement

Kidneys: hematuria, proteinuria, casturia, hypertension and edema, called purpuric nephropathy

Others: intracranial hemorrhage, epistaxis, gum bleeding, hemoptysis

diffuse abdominal pain

Arthritis or joint pain

Biopsy of any site showing deposits of IgA immune complexes

kidney damage

gastrointestinal bleeding

angioedema

severe arthritis

Fever (lasts 7-14 days and does not respond to antibiotic treatment)

Skin manifestations: erythema multiforme and scarlet fever-like rash, redness and peeling of perianal skin

Symptoms of hands and feet: acute stage: hard edema of hands and feet, erythema of palms and soles. Recovery period: membranous peeling appears at the junction of fingertips and skin

Hyperemia of the conjunctival membrane: no purulent secretions

Lip and oral manifestations: bleeding and chapped lips, diffuse congestion of oral mucosa, strawberry tongue

Cervical lymph node enlargement: the surface is not red and does not have suppuration, but may be tender to the touch.

Cardiac manifestations: Pericarditis, myocarditis, endocarditis, and arrhythmia may occur in 1-6 weeks. Coronary artery damage usually occurs within 2-4 weeks of the disease, but may also occur during the recovery period. Myocardial infarction and coronary artery aneurysm rupture can cause cardiogenic shock or sudden death.

Echocardiography is the most important auxiliary examination method: generally, coronary artery diameter >3mm is dilation, >4mm is aneurysm, and >8mm is giant aneurysm, which may even lead to coronary artery stenosis.

Changes in limbs: palmar and plantar erythema in the acute phase, hard edema of the hands and feet, and membranous peeling of the fingertips in the recovery phase

Polymorphic rash

Conjunctival congestion, non-suppurative

Congested and chapped lips, diffuse congestion of oral mucosa, strawberry tongue

swollen lymph nodes in neck

Use aspirin in combination with glucocorticoids. When glucocorticoids are useless, use aspirin in combination with glucocorticoids.