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This is a mind map about bacteria, and its main contents include: overview, morphology, types, structure, reproduction, distribution, application, and expansion. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about plant asexual reproduction, and its main contents include: concept, spore reproduction, vegetative reproduction, tissue culture, and buds. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about the reproductive development of animals, and its main contents include: insects, frogs, birds, sexual reproduction, and asexual reproduction. The summary is comprehensive and meticulous, suitable as review materials.
hyperprolactinemia
Definition and Overview
Hyperprolactinemia is a condition in which prolactin levels in the blood are abnormally elevated.
Prolactin is a hormone produced by the anterior pituitary gland and mainly regulates mammary gland development and milk secretion.
Hyperprolactinemia can be caused by a variety of factors, including physiological and pathological factors.
Cause
Physiological hyperprolactinemia
Physiological hyperprolactinemia often occurs in pregnant and lactating women.
Levels of prolactin produced by mammary gland stimulation increase during pregnancy and lactation.
Pathological hyperprolactinemia
Pituitary adenoma
Pituitary adenomas are the most common primary cause of hyperprolactinemia.
The adenoma compresses or destroys the prolactin-producing cells in the pituitary gland.
drug-induced hyperprolactinemia
Certain medications, such as antipsychotics and antidepressants, can cause elevated prolactin levels.
Other causes
Other pathological factors, such as thyroid dysfunction, renal dysfunction, etc., can also cause hyperprolactinemia.
Symptoms and signs
Symptoms of normal hyperprolactinemia
Normal physiological hyperprolactinemia in pregnant or lactating women generally has no obvious symptoms.
Symptoms of pathological hyperprolactinemia
Infertility and menstrual disorders
Hyperprolactinemia can inhibit gonadotropin secretion, affecting ovulation and menstrual cycles.
breast abnormalities
Prolactin promotes the proliferation of breast cells, causing breast enlargement or secretion of milk, which may even occur in infertile women.
Pituitary tumor compression symptoms
Hyperprolactinemia caused by pituitary adenoma is often accompanied by clinical manifestations of pituitary adenoma, such as headache, vision loss, etc.
Diagnosis and identification
Prolactin level testing
Blood tests can measure prolactin levels in the serum and help diagnose hyperprolactinemia.
Normal ranges vary between laboratories, but generally hyperprolactinemia in pregnant and lactating women can be considered physiologic.
Film degree exam
Brain magnetic resonance imaging (MRI) can detect pituitary adenomas and the presence of other causes.
Differential diagnosis
Hyperprolactinemia needs to be differentiated from postpartum hypothyroidism, ovarian insufficiency, renal dysfunction and other diseases.
Treatment and Management
basic treatment
Remove or treat the cause, such as surgery to remove a pituitary adenoma.
Adjust or discontinue medications that may cause hyperprolactinemia.
medical treatement
Most cases of hyperprolactinemia can be treated with medications to lower prolactin levels.
Commonly used medications include dopamine agonists and carbidopa hydrochloride.
Surgical treatment
For some causes that require surgical treatment, such as pituitary adenomas, surgical removal is a common treatment method.
Follow-up and management
Patients need to undergo regular prolactin level testing to monitor treatment effects and disease progression.
During follow-up, the treatment plan can be adjusted according to the patient's condition.