MindMap Gallery Medicine - Hypersensitivity
About medicine-hypersensitivity mind map, clinical immune testing technology, detailed introduction, comprehensive description, I hope it will be helpful to interested friends!
Edited at 2023-11-27 11:06:16This is a mind map about bacteria, and its main contents include: overview, morphology, types, structure, reproduction, distribution, application, and expansion. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about plant asexual reproduction, and its main contents include: concept, spore reproduction, vegetative reproduction, tissue culture, and buds. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about the reproductive development of animals, and its main contents include: insects, frogs, birds, sexual reproduction, and asexual reproduction. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about bacteria, and its main contents include: overview, morphology, types, structure, reproduction, distribution, application, and expansion. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about plant asexual reproduction, and its main contents include: concept, spore reproduction, vegetative reproduction, tissue culture, and buds. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about the reproductive development of animals, and its main contents include: insects, frogs, birds, sexual reproduction, and asexual reproduction. The summary is comprehensive and meticulous, suitable as review materials.
Hypersensitivity diseases and immune detection
Type I hypersensitivity reaction
allergic reaction anaphylaxis immediate hypersensitivity reaction
sIgE antibody
Detection
in vivo
skin test
Provocation test
Type ⅠⅣ
in vitro
tI
Immunoturbidimetric assay (macromolecule) CLIA ELISA (double-antibody sandwich method)
disease
respiratory tract
allergic asthma allergic rhinitis
digestive tract
allergic gastroenteritis
skin
angioedema urticaria eczema
Systemic
sIg
method
RAST RIA: an effective method for detecting type I hypersensitivity reactions
Western blot
cross-reactivity
Cause: Oligosaccharide side chain "CCD" in allergens of plant or animal origin - false positive
luciferase immunoassay
IgG4
cell degranulation
Protease-like (mast cell) Basophil degranulation Eosinophil cationic protein
Type II hypersensitivity reaction
Cytolytic (RBC) cytotoxic hypersensitivity reaction
Complement, phagocytes and NK cells are involved
Detection
anti-blood cell antibodies
Coombos
autoantibodies
Anti-acetylcholine receptor antibodies – myasthenia gravis Anti-thyroid stimulating hormone antibodies – hyperthyroidism Anti-glomerular basement membrane type IV collagen antibodies—pulmonary hemorrhage nephritis syndrome
indirect immunofluorescence test
disease
transfusion reaction
neonatal hemolysis
autoimmune anemia
Hyperthyroidism
myasthenia gravis
Pulmonary hemorrhage-nephritis syndrome
Type III hypersensitivity reaction
Immune complex type vasculitic type hypersensitivity reaction
Antigen-antibody bound moderately soluble immune complexes (circulating immune complexes CIC)
Congestion, edema, local necrosis, and neutrophil infiltration
Detection
PEG turbidimetry (physics)
disease (Infectious diseases and autoimmune diseases)
Arthus reaction: horse serum injected into rabbits
Systemic IC disease
Serum sickness: high-dose serum from xenogeneic animal sources
Streptococcal glomerulonephritis
Rheumatoid Arthritis
SLE (systemic lupus erythematosus)
Type IV hypersensitivity reaction
delayed immune disease
T cell mediated, independent of complement antibodies → mononuclear cell infiltration and tissue damage
Detection
Skin test
patch test
disease
Tuberculin skin test O-T
contact dermatitis
transplant rejection
infectious delayed hypersensitivity reaction
the difference
Types I-III are mediated by antibodies and passively transferred through serum
Type IV is mediated by T cells and passively transferred through cells