MindMap Gallery Medicine - Function mind map of various types of cytokines
This is a functional mind map about various types of cytokines in medicine. It summarizes and remembers the functions of important cytokines, including cytokines, cytokine receptors, etc.
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This is a mind map about bacteria, and its main contents include: overview, morphology, types, structure, reproduction, distribution, application, and expansion. The summary is comprehensive and meticulous, suitable as review materials.
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Functions of various types of cytokines💍
Cytokines
Interleukin IL
IL-1 (epidemic poison kills giant trees, hot white cancer)
Activate macrophages
Promote DC maturity
Induces CTL and NK cell killing
Stimulate inflammatory response, endogenous pyrogen, shock
islet inflammatory response
Stimulates the growth of leukemia cells, ovarian cancer cells
IL-2 (I [I] love [L2] talk about [T] him [T], swear to kill [turn poisonous bite] with tears in my eyes)
produce
T cells
Target position
T cells
effect
Promote T cell proliferation and differentiation
T cells produce IL-2 to stimulate the growth of T cells themselves
Activate cytotoxic lymphocytes
Activate macrophages
Promote NK cell killing effect
IL-3 (loose studies)
Induces early hematopoietic progenitor cells to differentiate and proliferate into a variety of blood cells
IL-4 (I love to death [4] Taobao [T] Taobao [TB], cut g love e shave T2 fat)
produce
T cells
Target position
T and B cells
effect
B cell growth factor, promotes antibody class switching to IgG1 and IgE
Stimulate T cell proliferation and differentiation into Th2
Stimulate mast cell proliferation
IL-5 (I help cut love, citric acid)
Enhanced IL-4-induced antibody class switching
Induces the production of IgA
Stimulates the differentiation of eosinophils into helminth-killing effector cells
IL-6 (I love Taobao, Darling, Beethoven, Hot, and I am grateful to him for helping me with cutting off love and myeloma)
produce
T, B, macrophage
Target position
B cells, liver cells
effect
Promote B cell differentiation
Promote CTL differentiation
Works with TGF-B to promote T cell differentiation towards Th-17
Enhanced IL-4-induced antibody class switching
Promote hepatic synthesis of acute phase proteins
Endogenous pyrogen, promote inflammatory response, shock
islet inflammatory response
autoimmune disease
Myeloma cells highly express IL-6R and secrete large amounts of IL-6
IL-7 (I love Qi Suizhi, he is my ex-boyfriend, and we are together again)
produce
bone marrow stromal cells
target cells
Pre-B cells, T cells
effect
Promote B cell and T cell proliferation
IL-8 (in inflammation)
Inflammatory response—chemotactic neutrophils
IL-10 (I love him who is honest, he is single-minded and restrains his philandering)
produce
T cells
target cells
Th1 cells
effect
Inhibits the synthesis of various cytokines
IL-11 (11 and a half)
For the treatment of thrombocytopenia
IL-12 (You love rats and kill them with all your heart)
produce
DC
target cells
T cells
Paracrine
effect
Promote T cell differentiation towards Th1
Inflammation
Promote NK cell killing effect
IL-15 (Foreign Object Massacre Kill)
Promote T cell proliferation and CTL killing
Promote NK cell proliferation and killing effect
IL-17 (encourage ourselves together)
autoimmune disease
IL-18 (you posted "He deserves the inflammation of his pancreatic islets, stupid")
Activate T cells and proliferate
islet inflammatory response
Promote NK cell killing effect
IL-23 (He encourages himself with his son)
Promote Th17 cell proliferation
autoimmune disease
colony stimulating factor CSF
G-CSF
M-CSF
GM-CSF
EPO
TPO
IFN
type I interferon
IFN-a (ah, giant forest, poisonous sand)
produce
Macrophages, lymphocytes, pDCs
Function
Antiviral
Stimulate expression of MHCI in virus-infected cells
Activate NK cells
IFN-B (no, toxic)
produce
Fibroblasts
Function
Antiviral
Stimulate expression of MHCI in virus-infected cells
type II interferon
IFN-y (Wow, there are many living TKs, such as reading a book or two, he is dedicated to preventing tumors and preventing love)
produce
Activated T cells, NK cells
Function
Activate macrophages, granulocytes, NK cells, T cells, and B cells
Stimulate expression of MHCI in virus-infected cells
Upregulating DC MHCI and II promotes antigen presentation
Induces T cells to differentiate into Th-1 subsets
Inhibit the growth of various tumor cells
Blocking IL-4-induced antibody class switching
tumor necrosis factor (TNF)
TNF-a (Alas TK is a huge fertilizer, grows trees in hot weather, fights tumors and kills pancreatic islets)
produce
Activated monocytes-macrophages/T cells/NK cells/mast cells
effect
Participate in anti-tumor
Endogenous pyrogen, mediates inflammatory response, shock
Promote DC maturity
autoimmune disease
Directly kill pancreatic islet cells
TNF-B/LT (lymphotoxin) (exogenous to B-boyfriend’s disease)
produce
activated T cells
effect
Antiviral
Mediates inflammatory response
Participate in the development of peripheral immune organs
Fas/FasL
Growth factors (GF)
Transforming growth factor (TGF) (transformed A)
Induces IgA production
Inducing T cells to differentiate into Treg
Inducing T cells to differentiate towards Th17
Vascular endothelial growth factor (VEGF)
effect
The growth and metastasis of cancer cells depends on the formation of new blood vessels
Cytokine receptor
Type I cytokine receptor family/hematopoietin receptor family (No. 180, 1521)
IL-2, 3, 4, 5, 6, 7, 9, 11, 12, 13, 15, 21
GM-CSF, G-CSF
Type II cytokine receptor family/interferon receptor family
IFN-a,B,y
IL-10
Tumor necrosis factor receptor family (neuroCD death)
TNF-a, B, FasL
CD40L
NGF (Nerve Growth Factor)
Immunoglobulin superfamily receptor (IgSFR)/IL1R family (your tail is scattered)
IL-1, 18, 33
M-CSF
IL-17 receptor family
IL-17
chemokine receptor family
Regulates the development and differentiation of immune cells in central immune organs
Bone marrow stromal cells secrete
IL-7, SCF, CXCL12
Regulates the development, differentiation and activation of immune cells in peripheral immune organs
Promote B cell activation, proliferation and differentiation into antibodies
IL-4, 5, 6, 13
Regulates class switching of Ig secreted by B cells
IL-4 induces the production of IgG1 and IgE
TGF and IL-5 induce IgA production
Promote T cell activation and proliferation
IL-2, 7, 18
Induces T cells to differentiate towards Th1
IL-12, IFN-y
Induces T cells to differentiate towards Th2
IL-4
Inducing T cells to differentiate into Treg
TGF-B
Inducing T cells to differentiate towards Th17
TGF-B, IL-6, 23
Promote CTL differentiation
IL-2, 6, IFN-y
Stimulate NK cell proliferation
IL-15
Stimulates the differentiation of eosinophils into helminth-killing effector cells
IL-5
Regulate the body's immune response
anti-infectious effect
antibacterial immunity
Macrophage release
IL-1, 6, 8, 12
IL-8 chemoattracts neutrophils into the site of infection
IL-1 and TNF-a promote DC maturation
TNF-a
Promote DC maturity
IFN-y upregulates the expression of DC MHCI and II molecules
antiviral immunity
IFN-a and B act on virus-infected cells and adjacent uninfected cells, inducing the production of anti-viral proteases
IFN-a, B, and y activate NK cells and promote their killing of virus-infected cells (early stage of infection)
IFN-a, B, and y stimulate virus-infected cells to express MHC class I molecules
IL-1, TNF-a and y activate monocytes/macrophages and enhance their phagocytic killing function
anti-tumor effect
TMFa and B directly kill tumor cells
IFN-y inhibits tumor cell growth
IL-1, 2, 15, IFN-y induce CTL and NK cell killing activity
IFN-y induces tumor cells to express MHCI
induce apoptosis
TNF-a induces apoptosis in tumor cells/virus-infected cells
Activated T cells express FasL and bind to Fas of target cells, inducing their apoptosis.
Immunosuppressive
IL-10
TGF-B