MindMap Gallery Connective tissue
The knowledge points of connective tissue in histology and embryology are characterized by fewer cells, more extracellular matrix, non-polar cells, blood vessels, nerves, and no basement membrane, and have functions such as support, connection, protection, nutrition, and defense.
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This is a mind map about bacteria, and its main contents include: overview, morphology, types, structure, reproduction, distribution, application, and expansion. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about plant asexual reproduction, and its main contents include: concept, spore reproduction, vegetative reproduction, tissue culture, and buds. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about the reproductive development of animals, and its main contents include: insects, frogs, birds, sexual reproduction, and asexual reproduction. The summary is comprehensive and meticulous, suitable as review materials.
connective tissue
Overview
Features
Few cells, more extracellular matrix, non-polar cells, blood vessels, nerves, and no basement membrane. Support, connect, protect, nourish, defend and other functions
source
Mesenchyme (mesenchymal cells and matrix) during embryonic stage
Classification
Broad meaning: liquid blood, lymph, soft intrinsic connective tissue and harder cartilage and bone
Narrow sense: intrinsic connective tissue
Loose connective tissue, dense connective tissue, reticular tissue, adipose tissue
loose connective tissue Widely distributed and many cell types, Fibers are few and scattered, rich in blood vessels and nerves, widely distributed and have many functions
cell
Fibroblasts
The largest and most important cells, often attached to collagen fibers Function: Synthesize and secrete collagen and elastin to form elastic fibers, reticular fibers, and collagen fibers Synthesis of secreted proteoglycans, which constitute the matrix Synthesis of bioactive substances involved in various processes LM: Large, protruding, large nucleus, light coloration, obvious nucleoli, weak basophilic cytoplasm EM: Abundant RER (rough endoplasmic reticulum) and well-developed GOL (Golgi apparatus) Functionally quiescent fibroblasts: LM, cells are small, long spindle-shaped, with small and elongated nuclei, light coloration, less cytoplasm, and eosinophilic
Macrophages
Mononuclear cells from the blood, with chemotaxis and directional movement capabilities, chemokines: bacterial products, inflammatory denatured proteins Phagocytosis: 1. Specific phagocytosis, recognition factor 2. Non-specific phagocytosis, no recognition factor required Secretion, lysosomes, complement, various cytokines antigen presentation LM: Pseudopodia, irregular shape, abundant cytoplasm, eosinophilic, small nucleus, dark staining, may contain foreign particles and vacuoles EM: There are microfolds or villi and globular protrusions on the surface, and the cytoplasm contains a large number of lysosomes, phagosomes, and residual bodies.
Plasma cell
Spleen, lymph nodes, digestive tract, respiratory tract and other mucosal connective tissue or lymphoid tissue and chronic inflammation sites LM: Oval, round nucleus, located on one side, heterochromatin is thick and wheel-shaped, the cytoplasm is basophilic, and there is a light staining area next to the nucleus EM: Rich RER and GC Function: Synthesize and secrete immunoglobulins (antibodies) to participate in immune response
Mast cells
Hematopoietic progenitor cells in the blood, often distributed along small blood vessels and small lymph nodes, such as connective tissue in the skin, digestive tract, and respiratory tract EM: The body is large, oval, the nucleus is small and round, located in the center of the cell, and the cytoplasm is filled with thick basophilic secretory granules. Synthesizes and secretes a variety of active mediators, which are related to allergic reactions
fat cells
LM: The body is large, round or polygonal, the nucleus is oblate and tilted to one side, and the cytoplasm contains a large lipid droplet. Function: Synthesize and store fat, participate in lipid metabolism
leukocyte
Source: Various white blood cells in blood Types: Neutrophils, Eosinophils, Basophils, Lymphocytes
Summary
Basophils: fibroblasts, mast cells, plasma cells Eosinophils: Macrophages Among them are mast cells, plasma cells, adipocytes, and white blood cells which are blood/immune/defense
fiber
Collagen fibers
Large amount of white fiber LM: pink, varying thickness, wavy, intertwined into a network EM: Composed of collagen fibrils, 67nm periodic striations Type I collagen, collagen. Fiber, high toughness, strong tensile strength
spandex
Small amount, yellow fiber LM: Eosinophilic, highly refractive, intertwined into a network Elastin, microfibrils (fibrillin) Great flexibility
mesh fiber
Argyrophilic fiber distribution network tissue, basement membrane LM: HE dyeing is light red, silver plating dyeing is black type III collagen
matrix Biological macromolecules constitute amorphous glue. Colorless, transparent, sticky, with tissue fluid in the gaps
Proteoglycans
Glycosaminoglycans (chondroitin sulfate, keratan sulfate, dermatan sulfate, heparan sulfate, hyaluronic acid) and glycoproteins Molecular sieve: allows tissue fluid to pass through and limits the spread of bacteria
fibronectin
Organic connection medium, affecting cell attachment and movement, regulating cell growth and differentiation. The most important of connective tissues
tissue fluid
Function: Constitutes an environment for cells to survive, creates/reflux obstacles, and causes tissue dehydration/edema.
dense connective tissue
Characteristics: There is a single type of cells, mainly fibroblasts, with many and thick fibers, densely arranged, and supporting connections.
type
regular dense connective tissue
A large number of densely packed collagen fibers arranged in parallel bundles, tenocytes
Irregular dense connective tissue
Distributed in dermis, dura mater and organ capsule Thick collagen fibers are intertwined vertically and horizontally, tightly arranged, and have fewer cells.
elastic tissue
Distributive ligaments, mainly elastic fibers, arranged in parallel bundles
Adipose tissue
Yellow (white) adipose tissue consists of single-vesicle adipocytes, stores energy, maintains body temperature, protects and fills, and secretes leptin
Brown adipose tissue: composed of multivesicular adipose tissue, found in newborns, producing energy in the interscapular area, armpits and back of the neck
reticular tissue
Reticular cells and reticular fibers Function: constitutes the basic component of hematopoietic tissue and lymphoid tissue, and provides a microenvironment for hematopoiesis and lymphocyte development.