MindMap Gallery Cell Biology
The molecular structure and characteristics of the cell membrane. The cell membrane is composed of membrane lipids (amphiphilic/facultative molecules), spherical molecular groups, bilayers, liposomes, membrane proteins, and membrane sugars.
Edited at 2023-07-27 11:28:17This is a mind map about bacteria, and its main contents include: overview, morphology, types, structure, reproduction, distribution, application, and expansion. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about plant asexual reproduction, and its main contents include: concept, spore reproduction, vegetative reproduction, tissue culture, and buds. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about the reproductive development of animals, and its main contents include: insects, frogs, birds, sexual reproduction, and asexual reproduction. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about bacteria, and its main contents include: overview, morphology, types, structure, reproduction, distribution, application, and expansion. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about plant asexual reproduction, and its main contents include: concept, spore reproduction, vegetative reproduction, tissue culture, and buds. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about the reproductive development of animals, and its main contents include: insects, frogs, birds, sexual reproduction, and asexual reproduction. The summary is comprehensive and meticulous, suitable as review materials.
Molecular structure and properties of cell membranes
chemical composition of cell membrane
Membrane lipids (amphiphilic/zwitterionic molecules) spherical molecular groups, bilayers, liposomes
Phospholipids: more than 50% of the head is hydrophilic and the tail is hydrophobic
Phosphatidylethanolamine (neutral)
Phosphatidylserine (negatively charged)
Phosphatidylcholine (neutral)
Sphingomyelin
cholesterol
Glycolipids (hydrophilic molecules)
Lipid and oligosaccharide composition
Monolayer located on the non-cytoplasmic side of the membrane
Membrane Protein
Membrane integral proteins 70%-80% (transmembrane proteins)
single transmembrane protein
multiple transmembrane proteins
multi-subunit transmembrane protein
Polypeptide chain is a helix
Lipatoxin
Two ways to combine
Peripheral membrane protein (20%-30%)
Such as erythroblastin on the surface of red blood cells and cytochrome CZ on the mitochondrial membrane.
membrane sugars
Form: glycoprotein or glycolipid
Cell coat or glycocalyx
Molecular structural model of cell membrane
lamellar structure model
unit membrane model
Liquid Mosaic Model
It is complemented by the lattice tessellation model and the plate tessellation model.
lipid raft model
Lipid rafts: rich in cholesterol and sphingomyelin
Characteristics of cell membrane
Asymmetry of the membrane (differences in structure and function between the inner and outer parts)
Asymmetry of membrane lipids: Phosphatidylserine is negatively charged (outer layer)
Asymmetry of membrane proteins: protein particles on the inner surface are larger than those on the outer surface
Sugar asymmetry
The oligosaccharide side chains of membrane glycoproteins or glycolipids are only distributed on the non-cytoplasmic surface (outside); the ATP binding point of the enzyme is on the inside; the hormone receptor is on the outside
membrane fluidity
Fluidity of membrane lipids (membrane lipid bilayer is liquid crystalline)
How membrane lipid molecules move
Rotation isomerism of hydrocarbon chains: C-C bonds can rotate freely
The stretching and oscillatory motion of fatty acid chains
Lateral diffusion movement: exchanging positions with neighboring molecules
rotational motion
Turning movement: flipping one layer of the lipid bilayer to another (flippase)
Factors affecting membrane lipid fluidity (Ambient temperature, ionic strength, PH, etc. Within a certain limit, as the temperature increases, the fluidity increases)
Length of fatty acid chain: the shorter, the more fluid
Degree of saturation of the fatty acid chain: the more double bonds, the lower the phase transition temperature and the greater the fluidity
Cholesterol: limits or increases membrane fluidity
The ratio of lecithin to sphingomyelin: the larger the ratio, the viscosity increases and the fluidity decreases
Membrane proteins: The more embedded proteins, the less fluid they are
membrane protein mobility
lateral diffusion
Rotational diffusion (slower)
Internal structure: grid shadow, microtubules fix membrane proteins, microfilaments cause membrane protein movement, cytoskeleton controls membrane proteins