MindMap Gallery B lymphocytes
The B lymphocyte map in medical immunology has the functions of producing antibodies to mediate humoral immunity, presenting antigens, and immune regulation. I hope this brain map will be helpful to you.
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This is a mind map about bacteria, and its main contents include: overview, morphology, types, structure, reproduction, distribution, application, and expansion. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about plant asexual reproduction, and its main contents include: concept, spore reproduction, vegetative reproduction, tissue culture, and buds. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about the reproductive development of animals, and its main contents include: insects, frogs, birds, sexual reproduction, and asexual reproduction. The summary is comprehensive and meticulous, suitable as review materials.
B lymphocytes
Differentiation and development
Surface molecules and their effects
B cell antigen receptor complex
composition
Membrane surface immunoglobulin (mlg)
lg α/ lg β (CD79a/CD79b) - can assist BCR to complete its function
Pattern diagram
Function
Receiving antigen stimulation to initiate an immune response
coreceptor
Category: CD19, CD21 and CD81 on the surface of B cells form B cell multi-molecular receptors
Pattern diagram
effect
1. Can enhance the stability of BCR and antigen binding
2.Co-transmit the first signal of B cell activation
costimulatory molecule
category
CD40——CD40 binds to CD40L on the surface of T cells to activate B cells important second signal
Pattern diagram
CD80 and CD86
Pattern diagram
Function: Binds to CD28 and CTLA-4 on T cells, A second signal that activates or inhibits T cells
adhesion factor
Th cells assist and activate B cells to present antigens to T cells requiring cell contact.
Function: Participate in the transmission of second signals and stimulate B cell activation
other molecules
Such as: CD19
CD20
CD22
CD32
Classification
Classification basis
According to activation status
naïve B cells
memory B cells
effector B cells
According to reaction type
Non-specific innate immune B cells: B1 Specific adaptive immune B cells: B2
According to BCR type
mIgM B cells: immature/naïve B cells. mIgG /mIgA /mIgE B cells: activated and class-switched B cells
Function
Antibody production mediates humoral immunity
Present antigen
Immunomodulatory