MindMap Gallery Essential hypertension mind map
Mind map of essential hypertension in internal medicine, summarizing the causes, pathogenesis, Pathology, clinical manifestations and complications, Laboratory and other tests, hypertension, Treatment etc.
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This is a mind map about bacteria, and its main contents include: overview, morphology, types, structure, reproduction, distribution, application, and expansion. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about plant asexual reproduction, and its main contents include: concept, spore reproduction, vegetative reproduction, tissue culture, and buds. The summary is comprehensive and meticulous, suitable as review materials.
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essential hypertension
Overview
High prevalence, low awareness, low treatment, and low control rates
A clinical syndrome characterized by increased systemic arterial pressure, affecting the structure and function of important organs, such as the heart, brain, and kidneys.
Blood pressure level classification and definition
Hypertension (SBP ≥ 140 and/or DPB ≥ 90)
Level 1 (mild)
140~159 and/or 90~99
Level 2 (mild)
160~179 and/or 100~109
Level 3 (mild)
≥180 and/or ≥110
isolated systolic hypertension
≥140 and <90
The diagnosis of hypertension must be based on three blood pressure measurements on different days without taking medication.
Cause
genetic factors
envirnmental factor
diet
obesity
mental stress
Pathogenesis
sympathetic nervous system activity
Activation of the renin-angiotensin-aldosterone system
Renal water and sodium retention
Impaired endothelial cell function
Insulin resistance
pathology
Thickening of the vessel wall, narrowing of the vessel lumen, and ischemic damage promote the formation and development of atherosclerosis.
heart
Left ventricular hypertrophy and enlargement, cardiomyocyte hypertrophy
brain
Cerebral lacunar infarction, which can cause blood vessel rupture and cerebral hemorrhage when pressure increases
kidney
Renal parenchymal ischemia, glomerular fibrosis and atrophy, chronic renal failure
retina
Can cause retinal hemorrhage and exudation
Clinical manifestations and complications
complication
hypertensive crisis
Hypertensive encephalopathy
cerebrovascular disease
heart failure
chronic renal insufficiency
Aortic dissection (blood seeps into the middle layer of the aortic wall to form a dissection hematoma), one of the causes of sudden death
Laboratory and other tests
Ambulatory blood pressure monitoring (recommended item)
Can diagnose white coat hypertension, masked hypertension, and evaluate medication status
risk stratification
No other risk factors and medical history: Level 1 low risk, Level 2 intermediate risk, Level 3 high risk
There are 1-2 risk factors: Level 1 moderate risk, Level 2 moderate risk, Level 3 very high risk
≥3 other risk factors and target organ damage: Grade 1 high risk, Grade 2 high risk, Grade 3 very high risk
Complications or diabetes: Level 1 is very high risk, Level 2 is very high risk, Level 3 is very high risk
cardiovascular risk factors
Men >55 years old, women >65 years old
smoking
Dyslipidemia
Family history of premature cardiovascular disease
Abdominal obesity (waist circumference ≥85cm for men, abdominal circumference ≥80cm for women), or body mass index (BMI) >28kg/m²
Blood homocysteine ≥10 μmol/L
impaired glucose tolerance
hypertension
Average ≥130/80mmHg, daytime ≥135/85mmHg, night ≥120/70mmHg
Normal high blood pressure fluctuates in a dipper pattern, with blood pressure falling by 10% to 20% at night.
abnormal blood pressure
Super dipper
Decline >20%
non-dipper type
Decline <10%
reverse dipper
No drops or more than daytime
treat
Reducing cardiovascular and cerebrovascular events is the fundamental purpose of lowering blood pressure. The general blood pressure control target value should be <140/90; for patients with diabetes, chronic kidney disease, heart failure, or stable coronary heart disease combined with hypertension, the control target value should be <130/80; systolic hypertension in the elderly should be controlled below 150
The low-risk group should improve their lifestyle and take medication if it is ineffective for six months; the intermediate-risk and high-risk groups should improve their lifestyle and take medication; the high-risk group should intensify treatment.
Improve lifestyle
antihypertensive medication
Principle: Start with a small dose, try to use long-acting preparations, and use combined medications
diuretics
Thiazides, loop diuretics (furosemide) deplete potassium (reduce extracellular fluid volume)
Potassium-sparing diuretics (spironolactone: an antagonist of the aldosterone system)
Patients with diabetes and hyperlipidemia should use it with caution, and patients with gout are prohibited from using it. Potassium-sparing diuretics can cause hyperkalemia (low dose recommended)
beta blockers
The antihypertensive effect is not strong, inhibiting central and peripheral RASS, inhibiting myocardial contractility, and slowing down the heart rate.
Suitable for mild to moderate hypertension, especially young and middle-aged patients with fast heart rate or hypertensive patients with angina pectoris, post-myocardial infarction and chronic heart failure patients
Contraindicated in acute heart failure, bronchial asthma, sick sinus syndrome, atrioventricular block, and peripheral vascular disease
Diabetic patients should use with caution
calcium channel blockers
Quick onset, strong effect, few adverse reactions (can cause enhanced sympathetic activity, increased heart rate, flushed complexion, headache, and lower limb edema)
Dihydropyridines: nifedipine
Non-dihydropyridines: verapamil and diltiazem
angiotensin-converting enzyme inhibitor
ARB
other