MindMap Gallery Monitoring and clinical application of respiratory function
The monitoring and clinical application of respiratory function in anesthesiology includes the main purpose of respiratory function monitoring, respiratory system physiology, respiratory function monitoring, etc.
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This is a mind map about plant asexual reproduction, and its main contents include: concept, spore reproduction, vegetative reproduction, tissue culture, and buds. The summary is comprehensive and meticulous, suitable as review materials.
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Monitoring and clinical application of respiratory function
The main purpose of respiratory function monitoring
Assess the patient's respiratory status
Diagnose the type and severity of respiratory dysfunction
Understand the dynamic changes in respiratory function of high-risk patients to facilitate disease assessment and adjustment of treatment plans
Evaluate the effectiveness of respiratory treatments
Ultimate goal: prevent hypoxemia and hypercapnia
Respiratory system physiology
breathe
Concept: It is the process of delivering oxygen to tissues throughout the body and expelling carbon dioxide
Three basic links
Pulmonary breathing (external breathing)
Pulmonary ventilation: the process of gas exchange between outside air and the lungs
Pulmonary ventilation: The process of gas exchange between the alveoli and pulmonary capillaries
Transport of gases in the blood
internal respiration or tissue respiration
The gas exchange process between blood, tissues and cells
hypoventilation
restrictive hypoventilation
Refers to alveolar hypoventilation caused by limited alveolar expansion during inspiration.
reason
Respiratory muscle activity disorder
Decreased thoracic compliance
Reduced lung compliance
Pleural effusion and pneumothorax
obstructive hypoventilation
Refers to ventilation disorders caused by airway narrowing or obstruction
Respiratory function monitoring
General monitoring
state of consciousness
Mild hypoxia - excited, multilingual, oriented
Severe hypoxia - confusion, drowsiness, coma
Skin and mucous membrane color
Reduced hemoglobin - cyanosis (except Hb<50g/L)
CO poisoning - cherry red
respiratory movement
frequency, amplitude, form
Chest auscultation, percussion, palpation
Ventilation function monitoring
static lung capacity
4 basic volumes
Tidal volume (VT) Inspiratory supplementary volume (IRV) expiratory supplementary volume (ERV) Residual volume (RV)
4 functional volumes
Vital capacity (VC) deep inspiratory volume Functional residual volume (FRV) total lung capacity (TLC)
dynamic lung volume
Minute ventilation (VE)
Total amount of air inhaled or exhaled per minute at rest
=Tidal volume VT×Respiratory rate RR
Alveolar ventilation (VA)
The amount of fresh air inhaled into the alveoli per minute
=(TV-Dead Cavity Amount)×RR
VA reflects the true gas exchange capacity of the lungs
Dead space
Physiological dead space/tidal volume (VD/VT)
Physiological dead space includes anatomical dead space and alveolar dead space
Maximum ventilation volume (MVV)
The maximum volume of air that can be exhaled or inhaled per minute while trying to breathe deeply and quickly
Evaluation of ventilatory reserve function
Forced vital capacity (FVC)
After the maximum inhalation, the maximum volume of air that can be exhaled at the fastest speed and with the greatest force
Forced expiratory volume (FEV)
Calculate the volume of air exhaled per unit time and the percentage of forced vital capacity occupied based on FVC
Maximum mid-expiratory flow (MMEF)
Concept: Calculate the average flow rate between 25% and 75% of forced expiratory vital capacity from the FVC curve.
Mainly affected by the diameter of the small airways, the decrease in flow reflects the obstruction of the small airways
Early detection of obstructive ventilatory dysfunction
ventilation function
blood oxygen monitoring
Arterial oxygen partial pressure (PaO2) and transcutaneous oxygen partial pressure (PtcO2)
Commonly used clinical indicators, reflecting arterial oxygenation and diagnostic criteria for hypoxemia
Arterial oxygen saturation (SaO2) and pulse oximetry (SpO2)
The latter is commonly used clinically, reflecting the various aspects of oxygen transport to tissues.
Mixed venous oxygen saturation (SvO2)
An indicator of the balance between oxygen supply and oxygen consumption
carbon dioxide monitoring
Arterial partial pressure of carbon dioxide (PaCO2): the pressure produced by physically dissolved CO2 molecules in the blood
Transcutaneous carbon dioxide partial pressure (PtcCO2): Generally higher than PaCO2 5~20mmHg
End-tidal carbon dioxide partial pressure (PETCO2)
Exhaled breath mass spectrometry
The significance of PETCO2 waveform changes
Elevated PETCO2
PETCO2 suddenly decreases
Sudden reduction to 0: respiratory circuit disconnection, endotracheal tube prolapse or accidental entry into the esophagus, sampling tube obstruction, etc.
PETCO2 decreases exponentially, seen in sudden drops in blood pressure, pulmonary embolism, cardiac arrest, etc.
A sudden decrease, but not reaching 0, may be caused by a twisted endotracheal tube or partial disconnection of the circuit.
CO2 waveform: continuously measured PETCO2 displayed on the monitor
Gas exchange efficiency monitoring
Alveolar air-arterial blood oxygen partial pressure difference
Understand the pathophysiological changes of hypoxemia and determine the cause of the disease
Oxygenation index (PaO2/FiO2)
Ventilation-perfusion index and respiratory failure index reflect oxygen exchange status
Oxygenation index <300mmHg, indicating pulmonary respiratory dysfunction
Intrapulmonary shunt (Qs/Qt)
Reflects whether the ratio of alveolar ventilation and blood flow is normal
In pathological conditions such as COPD, ARDS, congenital heart disease, right-to-left shunt, pulmonary edema, and atelectasis, the ratio of alveolar ventilation and blood flow significantly decreases, functional shunt increases, and Qs/Qt increases significantly, reaching 30 to 50% in severe cases.
Diffusion function measurement
Diffusion capacity (DL)
The amount of gas that can pass through the alveolar membrane under unit partial pressure difference (mmHg or kPa) within a certain period of time (1 minute)
It is a physiological index that measures the function of the alveolar membrane.
clinical significance
Reduce: extensive damage to lung tissue, pulmonary edema, pulmonary fibrosis, asbestosis, etc.
Increased: polycythemia, intracardiac left-to-right shunt
Oxygenation function monitoring
Ventilation function monitoring
blood gas analysis
Small airway function monitoring
Closing volume (CV)
The amount of air that can continue to be exhaled when the small airways in the lower part of the lung begin to close during one exhalation from the total lung capacity
CV/VC: Increased due to small airway obstruction or decreased elastic recoil of the lungs. Seen in long-term heavy smoking, bronchiolar infection, COPD, and interstitial pulmonary fibrosis
Maximum expiratory flow-volume curve (MEFV): maximum expiratory flow at 50% of vital capacity and maximum expiratory flow at 25% of vital capacity. Measured/estimated <50% is abnormal.
Dynamic lung compliance/static compliance ratio <0.8 indicates small airway disease
Respiratory mechanics monitoring
airway pressure
airway resistance
Chest and lung compliance
Pressure-Volume Ring (P-V Ring)
Flow rate-volume ring (F-V ring)
The normal work of breathing (WOB) is 0.4-0.6J/L
Clinical application
Preoperative respiratory function assessment and respiratory treatment