MindMap Gallery Perioperative blood management
Anesthesiology Chapter 11 Perioperative blood management, including treatment of anemia and optimization of red blood cell production, Measures to reduce perioperative blood loss, Perioperative red blood cell transfusion, etc.
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This is a mind map about bacteria, and its main contents include: overview, morphology, types, structure, reproduction, distribution, application, and expansion. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about plant asexual reproduction, and its main contents include: concept, spore reproduction, vegetative reproduction, tissue culture, and buds. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about the reproductive development of animals, and its main contents include: insects, frogs, birds, sexual reproduction, and asexual reproduction. The summary is comprehensive and meticulous, suitable as review materials.
Perioperative blood management
Treat anemia and optimize red blood cell production
Anemia: Hemoglobin (Hb) <130 for men, <120 for women, and <110g/L for pregnant women
Erythropoiesis-stimulating drug (ESA) therapy plus iron supplementation
Measures to reduce perioperative blood loss
Improvements and improvements in surgical techniques
controlled blood pressure reduction
intraaortic balloon occlusion
Maintenance of body temperature during surgery
Perioperative red blood cell transfusion
Open transfusion strategy
Restrictive transfusion strategy
Proposal and prospects of individualized blood transfusion strategies
red blood cell preparation
Concentrated red blood cells PRBC
Red blood cell suspension RBC
The most widely used
centrifuge
red blood cells additives
Leukocyte-poor red blood cells LPRC 24h
organ transplant blood transfusion
Wash red blood cells for 24 hours
centrifuge
red blood cells saline
Frozen red blood cells FTRC 10y
Blood Transfusion Guidelines (Red Blood Cells)
HB > 100g/L → generally no blood transfusion
HB < 70 g/L → Blood transfusion is required (especially acute anemia)
HB 70~100 g/L → blood transfusion? → Is there any risk of poor oxygenation?
Management of perioperative coagulation function
Plasma and plasma products
Fresh frozen plasma FFP
-20 degrees or less a year
Contains all plasma proteins and coagulation factors
Supplementing coagulation factors, large area trauma and burns
Cryoprecipitate: rich in factor VIII and fibrinogen, used to treat factor VIII deficiency, hemophilia A or fibrinogen deficiency
Prothrombin complex: contains factors II, VII, IX, and X
Fibrinogen preparations
albumin
Transfusion Guidelines (FFP)
PT or APTT>1.5 times normal, diffuse bleeding in the wound
Massive bleeding or blood transfusion (equivalent to the patient's own blood volume)
Congenital or acquired coagulopathy
Emergency anticoagulant effect of warfarin (5-8ml/kg)
It is prohibited to use FFP as a volume expander and to promote wound healing.
Usually after injecting a dose of 10-15ml/kg, most coagulation factors are increased to 25% of normal to effectively stop bleeding.
Most of the FFP currently used clinically have not been inactivated and are high-risk products for viruses.
Platelet preparations
Manual separation of platelet concentrates
Machine apheresis of concentrated platelets
Used for: bleeding caused by thrombocytopenia, bleeding caused by platelet dysfunction
Blood Transfusion Guidelines (Platelets)
>100×109/L→ Don’t lose
50*109/L ~ 100*109/L → discretionary
< 50*109/L → lose
Low function affects more than quantity
Fast and sufficient (same as cryoprecipitate)
Whole blood
Patients with massive blood loss may develop hypovolemic shock
perioperative autologous blood transfusion
Preoperative autologous blood reserve
Autologous blood recovery
acute isovolumetric hemodilution technique