yellow bone marrow

red bone marrow

Microenvironment

The place where various types of blood cells and immune cells occur

The place where B cells and NK cells differentiate, develop and mature

site of humoral immune response

cortex

medulla

Secretion of Cytokine Thymosin Peptide Molecules

cell to cell contact

The place where T cells differentiate and mature

Immunomodulatory

Establishment and maintenance of autoimmune tolerance

cortex

medulla

T cells, B cells colonization site

site of immune response

filtering effect

Participate in lymphocyte recirculation

white marrow

Red pith

fringe zone

T cells, b cells colonize

immune response

Synthetic biologically active substance, complement interferon

filter

Intestinal related

nasal related

bronchi

mucosal local immune response

secretory lgA