Transmembrane potential of cardiomyocytes in resting state

-80~-90mV (ventricular myocytes); -70mV (sinoatrial node P cells); -90mV (Purkinje cells)

A large amount of K outflow

A small amount of Na inflow

sodium pump activity

Transmembrane potential changes of ventricular myocytes during excitement

Period 0 (depolarization period)

Phase 1 (initial stage of rapid repolarization)

Phase 2 (platform phase)

Formation mechanism

Stage 3 (end of rapid repolarization)

Phase 4 (resting phase)

Transmembrane potential and formation mechanism of autonomous cells (such as sinoatrial node cells and Purkinje cells)

Features

Formation mechanism

P cell-specific If channel mediates

Features

Formation mechanism

Ion channels involved in the formation of transmembrane potential of cardiomyocytes and their functions

Mediates phase 0 depolarization

Mediates phase 1 rapid repolarization

Mediates Ca2 influx during phase 2 plateau

Mediates phase 2 and 3 K efflux

Mediates resting potential and late phase 3 K efflux

Mediates phase 4 automatic depolarization of sinus node cells