MindMap Gallery Chapter 6 Antipyretic, Analgesic and Anti-Inflammatory Drugs
Pharmacy major, drug technology mind map, antipyretic, analgesic and anti-inflammatory drugs, collectively known as non-steroidal anti-inflammatory drugs (NSAID), are a class of antipyretic, analgesic, and most also have anti-inflammatory, Anti-rheumatic drugs.
Edited at 2024-10-11 09:23:13Dive into the world of the Chinese animated film Nezha 2: The Devil's Birth! This knowledge map, created with EdrawMind, provides a detailed analysis of main characters, symbolic elements, and their cultural significance, offering deep insights into the film's storytelling and design.
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Dive into the world of the Chinese animated film Nezha 2: The Devil's Birth! This knowledge map, created with EdrawMind, provides a detailed analysis of main characters, symbolic elements, and their cultural significance, offering deep insights into the film's storytelling and design.
This is a mindmap about Nezha 2, exploring its political metaphors and cultural references. The diagram highlights the symbolism behind the Dragon Clan’s suppression, drawing parallels to modern geopolitical conflicts and propaganda manipulation. It also details Chinese historical and cultural elements embedded in the film, such as the Jade Void Palace, Ao Bing’s armor, Taiyi Zhenren’s magic weapon, and Nezha’s hairstyle.
This is a mindmap about the main characters of Nezha 2, detailing their backgrounds, conflicts, and symbolic meanings. It explores the personal struggles and transformations of Nezha, Ao Bing, Shen Gongbao, and Li Jing as they navigate themes of rebellion, duty, ambition, and sacrifice.
Chapter 6 Antipyretic, Analgesic and Anti-Inflammatory Drugs
Section 1 Overview
Mechanism of action of antipyretic, analgesic and anti-inflammatory drugs
It is a type of drug that has antipyretic, analgesic and anti-inflammatory effects and is mainly used to reduce fever and relieve chronic pain as well as anti-inflammatory and anti-rheumatic drugs.
The mechanism of action of antipyretic, analgesic and anti-inflammatory drugs is to block the biosynthesis of prostaglandins by inhibiting cyclooxygenase, thereby achieving antipyretic, analgesic, anti-inflammatory and anti-rheumatic effects.
Common adverse reactions to drugs
gastrointestinal injury
It is the most common adverse reaction of antipyretic, analgesic and anti-inflammatory drugs.
kidney damage
There are three main types, acute renal insufficiency, acute interstitial nephritis, chronic interstitial nephritis and renal papillary necrosis.
liver damage
Antipyretic, analgesic and anti-inflammatory drugs can cause hepatotoxicity and liver necrosis.
cardiovascular and cerebrovascular damage
Selective COX-2 logs should be like Selexibu, etc.
Other adverse reactions
Most antipyretic, analgesic and anti-inflammatory drugs can inhibit platelet aggregation, prolong bleeding time and cause rash, urticaria, exfoliative dermatitis, asthma, etc.
Section 2 Commonly used antipyretic, analgesic and anti-inflammatory drugs
Salicylates
Medication (aspirin)
Pharmacological effects
This product has excellent antipyretic, analgesic, anti-inflammatory and anti-rheumatic effects.
Indications
Analgesic, antipyretic, anti-inflammatory, anti-rheumatic, anti-thrombotic, pediatric use for the treatment of mucocutaneous lymph node syndrome (Kawasaki disease) in children.
adverse reactions
The more common gastrointestinal reactions include nausea and vomiting, upper abdominal discomfort or pain, gastrointestinal bleeding or ulcers.
Anilines
Medications (acetaminophen)
Pharmacological effects
The antipyretic and analgesic effect of this product is mild and long-lasting. The antipyretic and analgesic effect is equivalent to or slightly lower than that of aspirin, but it has no anti-inflammatory effect.
Indications
It is mainly used for patients with fever, headache, joint pain, rheumatic pain, neuralgia, dysmenorrhea and patients who are intolerant or allergic to aspirin.
adverse reactions
Adverse reactions are less common at therapeutic doses, including rash, anorexia, nausea and vomiting, methemoglobinemia, neutropenia, etc. occasionally.
Pyrazolones
Medications (Oxybuzone, Gamma-ketophenbutazone)
Arylalkanoic acids
Indoleacetic acids
Medication (Indomethacin)
Pharmacological effects
This product is one of the strongest COX inhibitors, with stronger anti-inflammatory and analgesic effects than aspirin.
Indications
It is mainly used for rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, cancer, fever and biliary colic, colic caused by urinary tract stones, etc. where salicylic acid has no obvious effect or is not easily tolerated.
adverse reactions
Gastrointestinal reactions may include loss of appetite, nausea, abdominal pain, upper gastrointestinal ulcers may occasionally perforate and bleed, and may also cause acute pancreatitis.
Arylacetic acids
Medication (Diflufenac Sodium)
Indications
Used for rheumatoid arthritis, neuritis, lupus erythematosus and cancer, post-operative pain, and fever caused by various causes.
adverse reactions
Can cause abdominal pain, diarrhea, nausea and other gastrointestinal reactions. Occasionally, headache, dizziness, and elevated aminotransferase may occur. Decreased kidney function is rare.
Arylpropionic acids
Medication (ibuprofen)
Pharmacological effects
The main action characteristics are similar to aspirin, and the incidence of certain adverse reactions is significantly lower than that of aspirin and indomethacin. It has strong antipyretic, analgesic and anti-inflammatory effects with few side effects.
Indications
It is suitable for rheumatism and rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and can also be used for general antipyretic and analgesic.
adverse reactions
Adverse reactions are mild, with occasional mild indigestion, rash, gastrointestinal ulcers and bleeding, increased aminotransferase, thrombocytopenia and blurred vision.
anthranilic acids
Medications (crefenamic acid, flufenamic acid, meclofenamic acid, clofenamic acid)
1,2-benzothiazines
Medication (meloxicam)
Pharmacological effects
It is a 1,2 benzothiazide non-steroidal anti-inflammatory drug with anti-inflammatory, analgesic and antipyretic effects.
Indications
For the treatment of rheumatoid arthritis, painful osteoarthritis (arthropathy, degenerative osteoarthrosis) and ankylosing spondylitis.
adverse reactions
Indigestion, abdominal pain, nausea, diarrhea, etc. are the most common.
Selective COX-2 inhibitors
Medication (celecoxib)
Pharmacological effects
Celecoxib is a selective inhibitor of COX-2 and is 375 times more selective for COX-2 than COX-1.
Indications
For acute and chronic osteoarthritis and rheumatoid arthritis.
adverse reactions
Common adverse reactions are epigastric pain, diarrhea and indigestion.