In the first half of the 20th century, the top three causes of death in developed countries were infectious diseases; in the second half, heart disease, cancer and stroke (autoimmune diseases) were replaced. The Hungarian doctor [Smelves], who discovered the cause of death from puerperal fever (sepsis), was persecuted by his peers and died of puerperal fever Civilization disease (autoimmune disease) originates from wealthy communities in developed and developing countries in Western countries; civilized disease does not affect a small number of wealthy people at the top of the pyramid (the rich can obtain the latest medical research information). All autoimmune diseases have the same time points in the surge. [28 Principle] Most of the immune tissues in the human body are distributed in the end of the small intestine, the cecum, and the appendix (the cause of appendicitis) [28 Principle] Autoimmune diseases are more common in women because women have stronger immunity than men, and the watershed during adolescence; autism little boys are 5 times that of little girls. The incidence of autism in Swedish-born Somalia immigrants is four times higher than that in Swedish children.

Magical garden warbler: gain weight by 10% every day, with specific rhythms (biological clock, intestinal flora, and in cages too); humans, like garden warbler, are gaining weight collectively, but they are gaining weight with garden warbler. Different causes. 2500 years ago, Hippocrates said: All diseases originate from the intestine. dysbiosis: Irritable bowel syndrome, antibiotic use after diarrhea and abdominal pain; the usual side effects of antibiotic use during chronic diarrhea. Germ-associated mice vaccinated with cecum contents of normal mice: eat less than usual, and increase weight by 60% in 14 days Obese people have a high proportion of Firmoid bacteria in the intestines; hunter-gathering bodies have a high proportion of Bacteroides in the body. Obese people (metabolic syndrome) are resistant to leptin, just as type 2 diabetes is resistant to insulin. Adenovirus 36 will make chickens fat. Get the same effect on monkeys. Ackermania mucophilin: There are 4% of these bacteria in the body of hunter-gatherer populations, but there are no fat people. This type of bacteria can help the intestine block microorganisms from entering the intestinal blood, thereby avoiding inflammatory reactions.

Changing the host's body and behavior is a way for organisms to increase their own evolutionary adaptability. In 1992, Canada, Andrew, who used antibiotics for a long time (because the ear canal was purulent), continued to use different types of antibiotics for 60 days, and developed autism: happy drunk, silent, extremely irritable, screaming all day, severe diarrhea Tetanus neurotoxin can reach the brain directly through the mivagal nerve. That should be more than just an abnormal substance, tetanus neurotoxin, which has the right to pass through the vagus nerve. serotonin, epinephrine, dopamine, oxytocin,

Allergies are negatively correlated with the number of infections during early childhood, and young children in a family of multiple children are less likely to be allergic (autoimmune) People in developed countries have very low probability of infecting parasites; the invasion of parasites makes the immune system busy with them, while the disappearance of parasites makes the immune system redundant and overreacts. Bacteroides fragile, polysaccharide A, regulates T cells, pro-inflammatory → anti-inflammatory Conjunctin = increased intestinal permeability: malt protein allergy, type I diabetes, Intestinal fistula is a necessary stage for autoimmune diseases

In 1944, the public began to use antibiotics, and in 1950, obesity began to appear in batches; farmers used antibiotics to make livestock fat. [Note] Since 2006, the EU has banned antibiotics for livestock. After 250,000 years of life without soap or fungicides: Sudden soap and fungicides will destroy the ecological balance of microorganisms In the late 1940s, American scientists accidentally discovered that injecting chickens with antibiotics could reduce their growth time by half. Cattle, pig, sheep, turkey, (geese, duck, rabbit), etc. have the same effect. Antibiotics can increase pig growth rate by 10% per day. Doctors use the same philosophy to treat infant malnutrition (thin) The same effect is also true for people, low doses of antibiotics and gain weight. Drug resistance: Staphylococcus aureus, methicillin-resistant Staphylococcus aureus, Clostridium difficile, [Notes] Clostridium difficile exists in every human body. It is reasonable to exist, imbalance or unreasonable. We humans have not yet discovered its usefulness. Just like Helicobacter pylori, nematode Clindamycin 7-day trial: Two years later, the community diversity of Bacteroides (such as Lactobacillus) in the subjects' intestines has not yet recovered. Ciprofloxacin (treatment of urinary tract infections and sinusitis): a 3-day course of treatment, and some bacteria cannot recover Vancomycin is used, and Lactobacillus reuteri (Posterior Gate) reproduces in large quantities due to drug resistance. Lactobacillus reuteri also secretes antibiotics to prevent the growth of other bacteria. It is not antibiotics that cause obesity, but changes in microbial ecology (gut microecology) caused by antibiotics Type I diabetes: cold or flu → antibiotic use → extreme thirst, extreme fatigue Minocycline, lupus erythematosus, is higher in women than in men. Minnesota, USA, production, addition and sales of static triclosan in 2017. Epidemic encephalitis: Streptococcus pharyngitis → Autoimmune response → Immune cells attack basal nucleus brain cells (basal ganglia)

During this period, I have been paying attention to probiotics, read five or six books on probiotics, and started using fermented foods and probiotic powders. Is the current behavior of probiotics summoning? Thinking becomes clearer, reading is more persistent. The proportion of high-fat foods increases → the proportion of Bifidobacterium decreases (Bifibacterium likes cellulose, prebiotic-oligosaccharides, and cannot be absorbed by the human body, but the foods of the probiotic Bifidobacterium): potatoes, bananas, asparagus, onions. Under prebiotic feeding: Bifidobacterium and Akkermansia muciniphila proliferate in large quantities; arataxyl herb (whole wheat fiber) Humans, leeches, bats, and giant pandas are similar in the symbiosis of intestinal microorganisms. Plant your own food, control the true nature of food, cook and eat by yourself Grow potatoes & storage, wheat & grinds, grow vegetables by yourself, brew soy sauce by yourself, grow chili by yourself, make kimchi by yourself, and a variety of fermented foods (sauce tofu, bean paste, fermented glutinous rice, kimchi, sauerkraut, cheese, yogurt, sour rice )

Not only do immune cells kill harmful bacteria, they are also responsible for transporting beneficial bacteria to places (through blood, lymph) where they should go. All animals pass on beneficial microorganisms to offspring: mother, cockroach mother (bacterial egg), hen (birth and digestive tract mixed), koalas (soft stool) Probiotic transplantation in the mother's birth canal and butt position: The changes in the probiotics in the birth canal before delivery, and the probiotics in the intestine should also change before delivery. The baby born with a natural birth is facing his mother's anus. Lactobacillus, Prevotella: Where Lactobacillus appears, there will be no pathogens, Bacillus difficile, Pseudomonas, and Streptococcus. Lactobacillus (lactic acid bacteria, the source of yogurt flavor) not only produces an acidic and hostile environment, but also produces an antibiotic of [bacterial] to kill competitors. Lactobacillus johnia (usually in the small intestine), produces enzymes that break down bile, produces a large amount of bacteriophagenins, and kills competitors. In the pregnancy stage, the value of women increases greatly. The bacterial diversity in the birth canal of pregnant women is reduced, as if it is carefully prepared for babies. The mortality rate of mothers with cesarean section is 13,000, and the mortality rate of mothers with 4 in 100,000 Children with caesarean section have twice as likely to suffer from obsessive-compulsive disorder than children with natural births There are more than 130 oligosaccharides in breast milk. Bifidobacteria decomposes oligosaccharides to produce various short-chain fatty acids: propionate, acetate, butyrate, and lactate, which are all foods for large intestinal cells. Dendritic cells are transporters of probiotics, from the mother's intestines, through the blood, and to the breast. The multiple armors that mother gives to the baby: the placenta is similar to the blood-brain barrier, the sterile uterus, the birth canal flora that hates evil, the natural feces, urine and fart inoculation, the mother's kiss, the dendritic cells that carry probiotics, colostrum (antibodies, prebiotics, Probiotics) The milk probiotics, prebiotics, and antibody components of mothers with emergency cesarean section (natural birth failure) are the same as those of mothers with natural birth, but they are different from those of mothers with direct cesarean section. Start the mechanism.

C. difficile, like one-third of the other bacteria living in the intestine, are like pathogens: produce spores. Resistant to antibiotics, stomach acid, cleansers, extreme temperatures. To see the effects of probiotics, prevention is better than treatment. Gene-deficient mice (diabetics) were fed probiotics every day, and the rate of diabetes in adulthood was 21%; 81% of the placebo-controlled groups were sick. Lizards, elephants, and rabbits all have feces, and chimpanzees treat diarrhea by using feces from healthy chimpanzees. In the 4th century, Ge Hong's "Emergency Preparation for Elbows", a beverage made of feces in healthy people can treat patients with food poisoning and severe diarrhea. Page (car accident, infected amputation, and a lot of long-term antibiotic treatment) is similar to Ermao's diarrhea, and the medicine can cure the disease. It is also scientific to cure the disease and repeatability. Rootcause may not be found; severe diarrhea caused by Clostridium difficile infection, the cure rate of multiple transplants of fecal bacteria is close to 100%, and there are no side effects, and the price is low. The way is simple. Use fecal transplant to treat any patient who may benefit from microbial ecological reconstruction. Fecal transplant is the most effective way to treat [irritable bowel syndrome]. The cure rate of constipation is only 30%. openBiome USA. Standard treatments and devices for diarrhea (including saline) for ordinary people. Bill, a patient with multiple sclerosis, originally used fecal bacteria transplant to treat constipation, but cured multiple sclerosis (amyotrophic cervix) 【Using fecal transplantation to eliminate insulin resistance】Effective; long-term probiotic prebiotics have the same effect.

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