Plague is an infectious disease caused by Yersinia pestis and is mainly transmitted to humans by fleas.

When the plague virus enters the body, it can cause severe systemic infection and cause symptoms such as high fever, swollen lymph nodes and difficulty breathing.

Patients with high suspicion of plague should receive early treatment immediately to prevent complications.

The goals of early treatment are to suppress the infecting pathogen and control symptoms to improve patient survival.

Antibiotics are the main early treatment, including quinolones, macrolides, and ofloxacin.

Antibiotic treatment is the mainstay of treatment for plague, rapidly suppressing the growth of the pathogen and controlling the infection.

Appropriate antibiotic treatment is selected based on the results of susceptibility testing to the pathogen.

Commonly used antibiotics include penicillin, tetracycline, and chloramphenicol, which can be administered orally or intravenously.

Antibiotic treatment generally lasts 10-14 days until symptoms resolve and body temperature becomes normal for 48 consecutive hours.

Plague patients also need to receive a series of supportive therapies during the treatment process to help them recover.

Supportive therapy includes rehydration, maintaining electrolyte balance, providing nutritional support and symptomatic treatment.

Fluid replacement is done through intravenous infusion to correct dehydration and electrolyte imbalance and maintain homeostasis.

Nutritional support is to provide sufficient energy and nutrients through diet or intravenous nutrition to promote the patient's recovery.

Prevention is an important part of plague control, including personal protection and epidemiological control.

Personal protection measures include avoiding contact with animals and fleas that may be infected with plague, and the correct use of protective equipment.

Epidemiological control measures include early detection of cases, isolation and treatment of patients, and tracing of close contacts.

Correct understanding of the transmission routes and prevention and control knowledge of plague, and strengthening publicity and education will help prevent the occurrence of plague.