The defense-based response of living tissues with vascular systems to damaging factors
inflammatory factors
Any factor that causes damage to organs, tissues, and cells can be a cause of inflammation
Cause
Physicochemical factors
physical factors
high temperature, low temperature, radioactivity
chemical factors
endogenous
Uric acid, urea
exogenous
Strong acid, strong alkali, poisonous gas
biological factors
Bacteria, viruses, spirochetes
Abnormal immune response
Basic pathological changes
spoil
Inflammation, degeneration and necrosis of local tissues
Morphological changes
parenchymal cells
Cellular edema
Steatosis
coagulative necrosis
liquefaction necrosis
interstitial changes
myxoid degeneration
fibrinoid necrosis
inflammatory mediators
cell-derived inflammatory mediators
Vasoactive amines
metabolite metabolite
white blood cell products
Cytokines
Nitric oxide
Plasma-derived inflammatory mediators
kinin system
complement system
coagulation and fibrinolytic systems
ooze
concept
The process in which the fluid components and cellular components in the blood vessels of local tissues of inflammation enter the tissue space, body cavity, mucosal surface or body surface through the blood vessel wall.
Hemodynamic changes
temporary constriction of arterioles
arterial congestion
venous congestion
fluid oozing
Increased vascular permeability
endothelial cell contraction
Enhanced cell penetration
endothelial cell damage
High permeability of new capillary walls
fluid oozing
Leukocyte extravasation
White blood cell edge set, Fubi
leukocyte adhesion
White blood cells swim out
Chemotaxis
The local role of white blood cells
Phagocytosis
Immunity
tissue damage
hyperplasia
Under the influence of pro-inflammatory factors, tissue cells in the inflammatory area proliferate through division, resulting in an increase in the number of cells.