Gastric cancer treatment mind map

This is a mind map about the treatment of gastric cancer, including endoscopic treatment, surgical treatment, chemotherapy, immunotherapy, etc.

Edited at 2023-11-17 16:29:43

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Gastric cancer treatment mind map

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Outline

Chapter 25 Gastric Cancer
- 121
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gastric cancer incidence
- 19
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stomach cancer
- 39
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Gastric cancer treatment

Endoscopic treatment

Endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD) is feasible for early gastric cancer

Surgical treatment

early gastric cancer

partial gastrectomy

Advanced gastric cancer

The scope of gastrectomy can be divided into proximal gastrectomy, distal gastrectomy and total gastrectomy. After resection, Billroth-I, Billroth-II and Roux-en-Y reconstruction are used respectively to maintain the continuity of the digestive tract.

If there is no distant metastasis, radical resection should be performed as much as possible.

For those with distant metastasis or obstruction, palliative surgery can be performed to keep the digestive tract open.

chemotherapy

Patients with early-stage gastric cancer without any metastases generally do not need chemotherapy after surgery.

Preoperative chemotherapy, that is, neoadjuvant chemotherapy, can shrink tumors and increase the chance of radical surgery and cure.

Postoperative adjuvant chemotherapy

It mainly includes intravenous chemotherapy, intraperitoneal chemotherapy, continuous hyperthermic intraperitoneal infusion and lymphoid targeted chemotherapy.

Commonly used drugs include fluorouracil (5-FU), tegafur (FT-207), mitomycin (MMC), doxorubicin (ADM), cisplatin (DDP) or carboplatin, nitrosoureas (CCNU) ,MeCCNU), etoposide (VP-16), etc. Combination chemotherapy usually uses 2 to 3 combinations to avoid increasing drug side effects. [1]

HER2 target therapy

[2]

Immunotherapy

Immunotherapy is a form of cancer treatment that uses the body's own immune system to fight cancer cells.

Passive immunotherapy is a form of treatment that uses antibody therapy to target cancer cells.

Active immunotherapy focuses on enhancing the body's immune response against tumor cells. Examples of active immunotherapy include vaccination and chimeric antigen receptors (CARs).

GC vaccine: including DC vaccine and DC cytokine-induced killer (DC-CIK) treatment, which uses DC to enhance the body's active immunity and achieve the purpose of prolonging the patient's survival. [3]