Sympatho-adrenergic medullary system excitement

Release of other humoral factors

maintain arterial blood pressure

Ensure blood supply to the heart, brain and other important organs

Pale complexion, clammy limbs, accelerated heart rate, and thin pulse

Accumulation of acidic metabolites

Increase in local vasodilator substances

The role of endotoxin

Hemorheology

Progressive decrease in blood pressure, decreased pulse pressure, and weak heartbeat

Blood rheology changes

The coagulation system is activated

Increase in procoagulant substances

Decreased function of the mononuclear phagocyte system

Etiology and pathogenesis

installment

According to the speed of occurrence

According to the body's compensation situation

clinical manifestations

changes in cell membrane

Mitochondrial changes

changes in lysosomes

apoptosis