MindMap Gallery Biochemistry Heptasaccharide Metabolism
Biochemistry for nursing students, summarizes the catabolism of glucose, gluconeogenesis, synthesis and decomposition of glycogen, Blood sugar and its regulation, etc.
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Avatar 3 centers on the Sully family, showcasing the internal rift caused by the sacrifice of their eldest son, and their alliance with other tribes on Pandora against the external conflict of the Ashbringers, who adhere to the philosophy of fire and are allied with humans. It explores the grand themes of family, faith, and survival.
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[Zootopia Character Relationship Chart] The idealistic rabbit police officer Judy and the cynical fox conman Nick form a charmingly contrasting duo, rising from street hustlers to become Zootopia police officers!
Glucose metabolism
Overview
Classification
Monosaccharide
Oligosaccharides
polysaccharide
bound sugar
Physiological function
Oxidation energy supply
Provide carbon source
important components of human body structure
special physiological functions
Provide biologically active substances
Digestion and absorption
glucose catabolism
anaerobic oxidation
concept
In anaerobic or hypoxic conditions, the process of decomposing glucose or glycogen to produce lactic acid in the cytoplasm
reaction process
first stage glycolysis
Second stage lactic acid production
Features
A dehydrogenation
Glyceraldehyde 3-phosphate—1,3-bisphosphoglyceric acid
Second production capacity
2 energy-consuming parts, 2 energy-producing parts, net production of 2 ATP
Three keys
Five points
Concept Reaction Conditions Part Stage Product
physiological significance
Quickly supply energy to the body
When oxygen is sufficient, some tissues and cells mainly rely on anaerobic oxidation to supply energy.
Provide raw materials for the synthesis of other substances
Aerobic oxidation
concept
Under aerobic conditions, glucose or glycogen is completely oxidized to synthesize Co2 and water.
reaction process
first stage glycolysis
Second stage oxidation of pyruvate to acetyl CoA
The third stage of the tricarboxylic acid cycle
subtopic
Features
primary substrate level phosphorylation
Two decarboxylation generates 2 molecules of Co2
three key enzymes
citrate synthase
isocitrate dehydrogenase
alpha-ketoglutarate dehydrogenase complex
three key enzymes
citrate synthase
isocitrate dehydrogenase
alpha-ketoglutarate dehydrogenase complex
decarboxylation four times
One cycle produces 10 molecules of ATP
physiological significance
A common pathway for complete oxidation of sugar, fat, and protein in the body
It is the hub of metabolism of sugar, fat and protein.
Intermediates of the Krebs cycle provide raw materials for other anabolic processes
products of aerobic oxidation
6 molecules of Co2
6 molecules of H2O
30 or 32 molecules of ATP
physiological significance
Aerobic oxidation is the main pathway for oxidative decomposition of glucose in the body
It is the main way for the body to obtain energy under normal circumstances.
Gluconeogenesis
reaction pathway
physiological significance
Maintain blood sugar levels relatively constant
Gluconeogenesis is an important way to replenish or restore liver glycogen stores
Helps maintain acid-base balance
Conducive to the reuse of lactic acid
Glycogen synthesis and breakdown
synthesis
Generation of living glucose UDPG
Glucose primordial transfer to glycogen primer
Glycogen branch formation
break down
The glycogen glycosides are phosphorolyzed starting from the non-reducing end.
Removal of glycogen branches
The breakdown of liver glycogen and muscle glycogen produces different products
physiological significance
Glycogen is an energy reserve substance in the body that can be quickly used
Help maintain a constant blood sugar concentration
Muscle glycogen breakdown provides much-needed energy for muscle contraction
Blood sugar and its regulation
source
Absorption of sugars from food
Glucose produced by liver glycogen breakdown
Non-sugar substances are converted into glucose through gluconeogenesis in the liver and kidneys
way out
Entering tissue cells for oxidative energy supply
Glycogen is synthesized and stored in tissues such as the liver and kidneys
Converted into fat and other substances
adjust
hormones that lower blood sugar
insulin
hormone that raises blood sugar
glucagon
Adrenaline
Glucocorticoids
high blood sugar
physiological
eating too much sugar
emotional
Recoverable
pathology
Insufficient secretion or impairment of insulin utilization
Hypoglycemia
physiological
chronic hunger
prolonged physical activity
Recoverable
pathology
Excessive secretion of insulinInsufficient secretion of insulin
When blood sugar is lower than 2.84mmol/L, it can seriously affect brain function and cause hypoglycemic coma.