In the early stage or when the disease worsens and relapses; local neutrophil infiltration, followed by replacement by macrophages and lymphocytes

Occurs when the collective resistance is strong and the disease is recovering; typical tuberculosis nodules

Microscopic examination shows red-stained, structureless granular material containing a lot of lipids, which appears light yellow to the naked eye and looks like cheese.

If you cough or expectorate for more than two weeks, or if there is blood in the sputum, a cavity is formed, or if it is combined with other infections, the sputum may be purulent.

Irritating cough: combined with bronchial tuberculosis

Hemoptysis: 1/3 patients have hemoptysis, most of which are small amounts of hemoptysis.

Chest pain: Accumulation of pleura

Dyspnea: caseous pneumonia, patients with massive pleural effusion

Fever: Prolonged afternoon hot flashes

Fatigue, night sweats, loss of appetite, weight loss

Signs of pulmonary consolidation (increased tremors, dullness on percussion, bronchial breath sounds, and fine crackles)

The trachea is displaced to the affected side, the chest cavity of the affected side is collapsed, dullness is present on percussion, breath sounds are weakened on auscultation, and bronchial breath sounds can be heard.

The trachea is displaced to the unaffected side, the chest on the affected side is full on inspection, the tactile fremitus is weakened, the sound is solid on percussion, and the breath sounds disappear on auscultation.

Chest X-ray is a common method, and CT can improve the resolution

Sputum specimen collection

Sputum smear test

Cultivation method

Drug sensitivity, other

More common in children and adolescents, with asymptomatic or mild symptoms; typical primary syndrome

More common in infants and teenagers; especially children with malnutrition and low resistance caused by long-term use of immune preparations

Acute miliary tuberculosis in adults: acute onset, persistent high fever, severe symptoms of poisoning; superficial lymph node enlargement, hepatosplenomegaly

Subacute and chronic disseminated type: slow onset, mild symptoms; uneven X-ray

Infiltrative pulmonary tuberculosis, cavitary tuberculosis, tuberculosis, caseous pneumonia, fibrocavitary tuberculosis, tuberculous pleurisy, other extrapulmonary tuberculosis, bacteria-negative pulmonary tuberculosis

Adult dosage: 300mg, qd/Children: 5~10mg/kg

Side effects: Occasional drug-induced hepatitis and peripheral neuritis can be treated with B6

It is recommended to take it on an empty stomach in the morning or half an hour before breakfast; the urine and urine will be orange-red after taking it.

Adults: 8~10mg/kg; children: 10~20mg/kg, 2 or 3 times a week

Side effects: transient transaminase elevation, jaundice, flu-like symptoms, skin syndrome, thrombocytopenia

Adults: 1.5g/d; children: 30~40mg/kg

Side effects: hyperuricemia, liver damage, lack of appetite, joint pain, nausea

Adults: 0.75~1.0g/d; not used for children

Side effects: Optic neuritis

daily medication

Intermission

Sensitive medication regimen

Intermission