A treatment method that collects blood or/and blood components for storage, or collects blood for processing when the patient is in a bleeding state, and then self-transfuses the blood or/and blood components when needed.

Avoid infectious diseases and immune transfusion reactions caused by allogeneic blood and blood components

Special groups (cross-incompatible, rare blood types, religious beliefs rejecting allogeneic blood, etc.) provide blood and blood components

Storage autologous blood transfusion can stimulate the differentiation of hematopoietic stem cells and promote red blood cell production

Diluted autologous blood transfusion can reduce the patient's blood viscosity and improve microcirculation

Provide a large source of blood, reduce the demand for allogeneic blood, and alleviate the tight blood supply situation

Stored Autologous Transfusion (PAD)

diluted autologous blood transfusion

salvage autologous blood transfusion

Weeks or even months before surgery, collect your own blood or blood components and store them for use during surgery.

Indications

Contraindications

The volume of blood collected at one time shall not exceed 500ml or 10% of the total blood volume of the self, and the maximum shall not exceed 12%.

The frequency of blood collection should be at least 3 days apart, and blood collection should be stopped 3 days before surgery.

Blood collection plan

local reaction

Fully assess the patient's potential for blood transfusion and do not recommend surgery with low possibility.

Develop a careful plan to decide whether to use erythropoietin (EPO) and other drugs

The blood transfusion department must have detailed patient medical records and important organ information

Label and register your own blood

Supplement iron, EPO, etc. 1 week before blood collection

Sign the informed consent form for autologous blood transfusion

By supplementing crystalloids and colloids to reduce the concentration of blood cells in unit volume of blood, the number of blood cells lost and the amount of bleeding can be significantly reduced during the same amount of surgical bleeding.

Indications

Contraindications

Comprehensive assessment of blood collection volume based on patient age, weight, main visceral function, type of surgery, expected blood loss, etc.

The blood collection volume is calculated based on 10% to 15% of the patient's total blood volume. If the patient is in good health, it can reach 20% to 30%.

The maximum dilution limit is that Hct is 0.20 and Hb is 65g/L after dilution

Infused back to the patient before the end of surgery or after surgery

systemic reaction

bleeding tendency

red blood cell agglutination

Under anesthesia, the effect of muscle relaxants can expand the peripheral blood circulation system. Pay attention to replenishing fluids to maintain effective circulating blood volume.

The red blood cells lost in the patient's own blood are basically normal, have not been damaged or contaminated, and can be reused after recovery.

According to recycling treatment method

By recycling processing time

Indications

Contraindications

bleeding tendency

Hemoglobinemia, renal insufficiency

pulmonary dysfunction

Disseminated intravascular coagulation (DIC)

Bacterial infection, sepsis

other

Blood recovered during surgery must not be transferred to other patients for use.

In the blood recovered during the operation, platelets, coagulation factors, and plasma proteins are basically lost. Platelets and coagulation factors should be replenished according to the amount of recovered blood.

The recovered blood that has not been washed contains a large amount of anticoagulant, and the corresponding antagonist should be given according to the amount of anticoagulant used.

Patients who undergo intraoperative salvage autologous blood transfusion should use antibiotics routinely after surgery

A blood transfusion device must be used when recovering blood for reinfusion

Minimal contamination of the surgical field, best indications for dilution autologous blood transfusion and salvage autologous blood transfusion

Minimum standards for blood dilution: Hct not less than 20%, Hb not less than 60g/L

Combined use of stored autologous blood transfusion and recovery autologous blood transfusion

Intraoperative salvage autologous blood transfusion

Use irradiation technology (25~30Gy) to process and recover washed red blood cells to kill tumor cells

Intraoperative salvage autologous blood transfusion is a safe and effective blood transfusion method for patients with bleeding after ectopic pregnancy

Autologous blood transfusion using continuous circulatory system

Use a variety of methods and drugs to dilate blood vessels, actively reduce vascular pressure in the surgical area, and reduce bleeding.

After anesthesia, before surgery or before extracorporeal circulation, drugs that act on the coagulation and fibrinolytic systems are selectively or preventively applied to inhibit the reaction of blood components so that they cannot be activated and remain in a "hibernation state" for recovery and "awakening" after surgery.

The commonly used blood anesthetic is aprotinin, which can reduce surgical bleeding by 54.8%.

EPO treatment requires at least 5 days to increase RBC, Hb, Hct and reticulocytes

EPO is combined with preoperative autologous stored blood to collect more autologous blood.