Hypothyroidism, for short, refers to systemic hypometabolic syndrome caused by hypothyroidism or thyroid hormone resistance due to various reasons, which manifests as myxedema.

Hypothyroidism originating in the fetus or newborn - cretinism, also known as cretinism, is often accompanied by intellectual disability and developmental delay.

Autoimmune damage is the most common cause

Thyroid destruction: surgery, iodine 131 treatment.

hypometabolic syndrome

Psycho-nervous system: prominent symptoms of drowsiness and slow reaction. Severe cases include dementia, hallucinations, lethargy, and convulsions.

Skin changes: Myxedematous appearance. Myxedema of the skin (non-pitting) is common around the eyes, on the dorsum of the hands and feet, and in the supraclavicular fossa. The voice is low and hoarse, the expression is dull, and the skin is dry, flaky and cold. The outer 1/3 of the eyebrows fell off. The skin of the hands and feet is ginger-yellow.

Muscles and joints: progressive muscle weakness and atrophy.

Cardiovascular system: Myxedema leads to heart enlargement, hypothyroid heart disease, and those who have been ill for a long time are prone to coronary heart disease.

Blood system: anemia.

Digestive system: fear of food, bloating, constipation, severe paralytic ileus or myxedema megacolon

Endocrine reproductive system: long-term can lead to hyperprolactinemia and galactorrhea. Growth retardation in children. Severe hypothyroidism in women leads to increased menstrual bleeding and ovulation disorders.

Myxedema coma: onset when cold. The trigger is stress. Lethargy and hypothermia are life-threatening due to heart and kidney failure.

Decreased high-density lipoprotein, normocytic normochromic anemia

Reduced TT4 and FT4 are necessary indicators for diagnosis. Serum TSH is the most sensitive and early first-line indicator for evaluating primary thyroid dysfunction. TT3 and FT3 are normal in the early stage and decreased in the late stage.

The TRH stimulation test is used to differentiate between pituitary hypothyroidism and hypothalamic hypothyroidism. If it is not increased, it is pituitary; if it is delayed, it is hypothalamic.

alternative treatment

Symptomatic treatment: supplement whatever is needed. Low gastric acid supplement dilute hydrochloric acid - combined with L-T4

Treatment of subclinical hypothyroidism: L-T4 treatment - as long as there is hypercholesterolemia and serum thyroid-stimulating hormone is greater than 10mU per liter.

Treatment of Myxedema Coma

constipate

hypothermia

Potential complications: Myxedema coma

Overweight/Obesity: Intake greater than needs and low metabolic rate

Inability to move

sexual dysfunction

Medication guidance