rising platelets

Myelosuppression after chemotherapy

Replenishing qi and solidifying phlegm, nourishing yin and promoting fluid production, and generating pulse; Improve immunity, enhance the effectiveness of chemotherapy drugs, and reduce side effects

Various types of acute felinitis, MDS, chronic granuloma, Polycythemia vera also has a certain effect

Divided into 2 parts, spaced 2.5cm apart

NS 100ml [IVgtt] Gemcitabine hydrochloride 1.5g

5%GS 500ml [IVgtt] Oxaliplatin 150mg

Prevention and treatment of infection, prevention and treatment of hyperuricemic nephropathy Correct anemia, control bleeding, and maintain nutrition

"VIP"(VDP/VDLP) ♦Central infiltration→Intrathecal injection of methotrexate ♦Testicular infiltration→One side infiltration, bilateral radiotherapy

"Acute large (DA) fruit" (IA/HA)

♦Preferred targeted therapy: imatinib, hydroxyurea ♦The most effective radical cure: bone marrow transplantation

♦Hydroxyurea: reduce leukocytes ♦Sodium bicarbonate: alkalizes urine ♦Allopurinol: lowers uric acid ♦Hydration and rehydration

Day 1

Day 2

Day 1

Day 2

NS 2ml intrathecal injection

Dexamethasone sodium phosphate 5mg intrathecal qd

Methotrexate 10 mg intrathecal qd

Cytarabine 0.05g intrathecal injection qd

Shenmai

Glutathione

sodium bicarbonate

methotrexate

Calcium leucovorin

Furosemide (furosemide)

Dexamethasone sodium phosphate 2.5mg [IV] q12h

NS 500ml [IVgtt] q12h Cytarabine 3g

NS 100ml [Ivgtt] Tropisetron hydrochloride 5mg

5%GS 250ml [Ivgtt] qd Glutathione 1.8g

NS 100ml [IVgtt] bid Omeprazole sodium 40mg

Arsenic trioxide 10mg [Ivgtt] qd 4 bottles

Retinoic acid 20mg bid for 2 weeks

Compound Huangdai Tablets 4# tid for 4 weeks

Bone marrow hematopoietic stem cell failure → reduction of three lineages, normocytosis

♦Drugs (most common): chloramphenicol and benzene cause immune damage ♦Viral infection (hepatitis virus, parvovirus B19), X-ray, etc.

①Hematopoietic stem and progenitor cell defects (seeds): CD34⁺↓↓

②Abnormal hematopoietic microenvironment (soil): fatification

③Immune abnormalities: Main (bug) CD8⁺↑↑

Correct anemia, control bleeding, control infection, and treat liver protection

♦Emergency: intracranial hemorrhage (PLT＜20*109/L)→platelet transfusion treatment

Chronic aplastic anemia: 80% of symptoms are relieved after treatment Severe aplastic anemia: (cerebral hemorrhage and severe infection) death within months to 1 year

Aplastic anemia: excessive iron input due to repeated blood transfusion → iron excess anemia Not supplementing iron, but too much iron. Clean up the iron.

To relieve anemia in hemolytic anemia → transfusion of washed red blood cells is the first choice. PNH requires transfusion of white blood cells and red blood cells

Hereditary spherocytosis, thalassemia with hypersplenism, Warm antibody type autoimmune anemia

Severe ITP: PLT＜20×109/L→intracranial hemorrhage

Non-severe ITP: PLT＞20×109/L→no blood transfusion

♦Those with severe bleeding should rest, platelets should be less than 20, and should stay in bed strictly. ♦No obvious bleeding, platelet count >30, observe

♦glucocorticoids → first choice ♦Intravenous globulin (IVIg): ITP emergency patients; complicated by pregnancy or Before delivery; intolerance to corticosteroids/pre-splenectomy preparation

♦Splenectomy ♦Immunosuppressants (vincristine), platelet production drugs

Three-pronged approach→platelet transfusion (first choice in emergency), Intravenous injection of C-ball and large amounts of methylprednisolone

♦Preferred: ABVD solution (Adriamycin, bleomycin, vincristine, methamphetamine) ♦Second choice: MOPP solution (nitrogen mustard, vincristine, procarbazine, prednisone)

♦Preferred: CHOP plan (cyclophosphamide, doxorubicin, vincristine, prednisone) ♦R-CHOP solution That is, rituximab is given before CHOP regimen

♦No bone marrow transplant: MP (melphalan, prednisone) and T (thalidomide) are preferred ♦Deciding to bone marrow transplantation: VD (bortezomib and dexamethasone) is the first choice

♦Bone pain → Bisphosphonates (inhibit osteoclasts) ♦Hypercalcemia, anemia, renal failure