The human body cannot synthesize folic acid. The folic acid required must be supplied by food. The required amount is about 200μg/d

The absorption site is mainly in the duodenum and proximal jejunum

The storage amount of folic acid in the human body is about 5-20mg, and nearly 50% is in the liver

Folic acid is mainly excreted from the body through urine and feces, and 2-5μg is excreted every day

It is an indispensable important substance in the biosynthesis and energy metabolism of the body

Normal people need 1μg per day, and the storage capacity in the human body is 2-5mg, of which 50-90% are in the liver

Mainly derived from animal liver, kidney, fish, meat, eggs and dairy products

Mainly excreted from the body through feces and urine

Folic acid deficiency: increased demand or insufficient intake

Vita12 deficiency: related to absorption disorders caused by gastrointestinal dysfunction

It is an important coenzyme in the human body. Lack of the DNA synthesis disorder can affect the

General manifestations of anemia Severe cases will experience repeated infections and bleeding

Early gastrointestinal mucosa involvement can cause appetite deficiency Nausea Abdominal bloating Diarrhea or constipation

Some patients have glossitis, angular stomatitis can cause "beef-like tongue"

Symmetrical distal limb numbness Deep sensory disorder

People with folic acid deficiency have irritability, paranoia and other mental symptoms

VitaB12 deficiency has depression, memory loss, etc.