Blocks the pupillary sphincter M receptor, and the pupillary sphincter relaxes, allowing the pupillary dilator muscle (α receptor) innervated by adrenergic nerves to dominate, and the pupil dilates.

The pupil dilates, the iris retreats to the periphery, the anterior chamber angle gap becomes smaller, hindering the return of aqueous humor into the scleral sinus, and the intraocular pressure increases

Block the M receptor of the ciliary muscle, the ciliary muscle retreats to the surroundings, the suspensory ligament becomes tense, and the curvature of the lens decreases, resulting in unclear vision of near objects and clear vision of distant objects.

Therapeutic doses slow heart rate

A larger dose blocks the sinoatrial node M2 ​​receptor, relieves the inhibitory effect of the vagus nerve on the heart, and accelerates the heart rate.

Therapeutic doses of atropine have no significant effect on blood vessels and blood pressure, but can completely antagonize the peripheral vasodilation and decrease in blood pressure caused by choline ester drugs.

Large doses of atropine can dilate blood vessels in the skin, causing the skin to become flushed and warm.

Treatment of gastrointestinal colic and bladder irritation, enuresis in children

Used with opioid analgesics to treat biliary colic and renal colic

Eye drops relax the iris pupillary sphincter and ciliary muscles, take adequate rest, and subside inflammation

Use alternately with miotic drugs to prevent iris and lens adhesion

Adjust paralysis and fix lens

Dilated pupils, fundus examination

Treat sinus bradycardia, sinoatrial block, atrioventricular block and other slow arrhythmias

Treatment of sinus or atrioventricular bradycardia associated with early myocardial infarction

Pay attention to dosage

Poor efficacy against ventricular arrhythmias

Pharmacological effects

Clinical application

Synthetic antispasmodic drug, incomplete absorption after oral administration, take before meals

Pharmacological effects

Clinical application

Mainly treats gastrointestinal diseases

Relieve gastrointestinal spasm and assist in the treatment of peptic ulcer

Relieve gastrointestinal spasm and assist in the treatment of peptic ulcer

Relieves smooth muscle spasm, inhibits gastric juice secretion, and has a central sedative effect

For ulcer patients with anxiety disorders

Selective effect on bladder

Treating Overactive Bladder

Non-specific direct relaxation of smooth muscle

Dicyclovirine: used for smooth muscle spasm, hyperperistalsis, peptic ulcer

Flavonoids and oxybutynin: have a selective effect on the bladder and treat overactive bladder