G-not easy to dye, commonly used Giemsa dyeing (purple red)

There is a microcapsule-like protein layer on the surface of the membrane, composed of polyproteins OmpA and OmpB, which has adhesion to host cells and anti-phagocytic effects.

Asexual binary fission reproduction: animals, chicken embryos, tissue cell culture

Different species of rickettsia have different locations within host cells

Group-specific antigen—lipopolysaccharide

Species-specific antigen—outer membrane protein

Waipei reaction

56℃, can be killed in 30 minutes

High sensitivity to tetracycline and chloramphenicol

Sulfa drugs are prohibited (can stimulate the growth of rickettsiae)

Resistant to drying

Rash, fever, headache, hepatosplenomegaly

Invasion site

Lipopolysaccharide (mainly)

Adhesins OmpA and OmpB

Phospholipase A

type IV secretion system

cellular immunity

popular link

Source of infection—human lice

route of infection

disease

popular link

Source of infection—rat, patient

Transmission vector—rat fleas, human lice

route of infection

Disease caused

popular link

Source of infection

media

route of infection

Disease caused

Transmitted by tick bite

human granulocytic anaplasmosis

Transmitted by tick bite

human monocytic ehrlichiosis