Chinese: T cell antigen receptor

Structure: a heterodimer composed of two peptide chains connected by disulfide bonds. Most T cell TCRs are composed of two peptide chains, α-β.

Function: The V region composed of two peptide chains together forms a conformation complementary to the antigen, and recognizes the antigen peptide on the APC or target cell membrane.

After TCR activation, itam phosphorylation transmits the signal into the cell

Function: transmit signals; stabilize the structure of TCR

Provides the second signal for T cell activation, promotes the proliferation of T cells, and the synthesis of IL-2

Enhance adhesion and provide costimulatory signals

Provide costimulatory signals for B cell activation

TOLL-like receptor

mannose receptor

scavenger receptor

Mannose-binding lectin

C-reactive protein

lipopolysaccharide binding protein

Phagocytosis and killing of pathogens

Mediates inflammatory response

Processing and presentation of antigens initiates adaptive immunity

Immunomodulation: secretion of cytokines to activate T cells

Mainly sterilization

Anti-tumor, anti-infection

Immunomodulatory effect