MindMap Gallery blood and hemogenesis
This is a mind map about the generation of blood and blood cells. Blood and blood cells are indispensable and important components of the human body. Their generation and physiological functions are of great significance to maintaining the health of the human body.
Edited at 2024-02-05 18:15:13Avatar 3 centers on the Sully family, showcasing the internal rift caused by the sacrifice of their eldest son, and their alliance with other tribes on Pandora against the external conflict of the Ashbringers, who adhere to the philosophy of fire and are allied with humans. It explores the grand themes of family, faith, and survival.
This article discusses the Easter eggs and homages in Zootopia 2 that you may have discovered. The main content includes: character and archetype Easter eggs, cinematic universe crossover Easter eggs, animal ecology and behavior references, symbol and metaphor Easter eggs, social satire and brand allusions, and emotional storylines and sequel foreshadowing.
[Zootopia Character Relationship Chart] The idealistic rabbit police officer Judy and the cynical fox conman Nick form a charmingly contrasting duo, rising from street hustlers to become Zootopia police officers!
Avatar 3 centers on the Sully family, showcasing the internal rift caused by the sacrifice of their eldest son, and their alliance with other tribes on Pandora against the external conflict of the Ashbringers, who adhere to the philosophy of fire and are allied with humans. It explores the grand themes of family, faith, and survival.
This article discusses the Easter eggs and homages in Zootopia 2 that you may have discovered. The main content includes: character and archetype Easter eggs, cinematic universe crossover Easter eggs, animal ecology and behavior references, symbol and metaphor Easter eggs, social satire and brand allusions, and emotional storylines and sequel foreshadowing.
[Zootopia Character Relationship Chart] The idealistic rabbit police officer Judy and the cynical fox conman Nick form a charmingly contrasting duo, rising from street hustlers to become Zootopia police officers!
blood and hemogenesis
blood
Blood is a special connective tissue
Blood cells (formed components)
Red blood cells (3.5~5.5×10*12/L), accounting for about 43% of the total
White blood cells (4.0~10×10*9/L)
Platelets (100~300×10*9/L)
Plasma (intercellular substance)
The main component is water, accounting for 55-56% of the total
Fibrinogen Thrombin>Fibrin
red blood cellsRBC
Biconcave disc shape - increases the surface area of red blood cells and facilitates gas exchange Mature red blood cells have no nuclei, no organelles, and the cytoplasm is filled with hemoglobin - which combines and transports oxygen and carbon dioxide Morphological variability
Hemolysis: Blood Shadow Bleeding: RBCs flowing out of blood vessels Anemia: RBC<3×10*12/L: Hb<100g/L
ABO blood type - based on whether there are specific receptors on the surface of the red blood cell membrane
Average lifespan 120 days
Reticulocytes: immature red blood cells with the ability to synthesize hemoglobin
white blood cellsWBC
nucleated, spherical Exit blood vessel execution function
Depending on whether there are special particles
granulocytic leukocytes
neutrophils
The nucleus is rod-shaped or lobed. The more lobes, the older it is.
Leftward shift of the nucleus: increased number of cells with nuclei or rod-shaped nuclei in 1 to 2 lobes, severe bacterial infection Nucleus shift to the right: increased nuclear cells in the 4th to 5th lobes, and bone marrow hematopoietic function is hindered
Contains
Light red special particles
Blue-purple azurophilic granules (lysosomes)
Function (similar to macrophages)
Metamorphosis, chemotaxis, phagocytosis (bactericidal)
After killing the cells, they die and become pus cells
basophils
Nucleus lobed, S-shaped or irregular Contains basophilic particles, blue-purple, which can cover the nucleus Can release histamine, leukotrienes, neutrophil chemotactic factors, eosinophil chemotactic factors, etc. to initiate inflammatory response
Stays in the blood for 6 to 7 hours and survives in tissues for 2 to 3 days
eosinophils
Core often 2 leaves The cytoplasm is filled with thick and uniform eosinophilic granules Anti-allergic and parasitic
Stays in blood for 6 to 8 hours and survives in tissues for 8 to 12 days
agranulocytosis (Contains azurophilic granules) Basophilic
Lymphocytes
There is a shallow depression on one side Lysosomes, RER, GC, mitochondria Potentially disruptive
According to their shape and size, they are divided into large, medium and small lymphocytes. Most of the blood cells are small lymphocytes.
Divided into T, B, and NK cells according to their origin and immune function
monocytes
Kernel-shaped or horseshoe-shaped peroxidase, nonspecific esterase Phagocytic vacuole, mitochondria, rough endoplasmic reticulum
platelets
Biconvex flat disk, no core
Granule area (center): blue-purple granules
special particles
Dense particles
Transparent area (peripheral part): light blue
microtubule-containing microfilaments
Life span 7 to 14 days
Normal value: 100~300×10*9/L
Bone marrow and hematopoiesis
marrow
red bone marrow
Filled with hematopoietic tissue and sinusoids, hematopoiesis
yellow bone marrow
Contains a lot of adipose tissue and has hematopoietic potential
Hematopoietic stem cells (pluripotent stem cells)
Originates from the blood islands in the yolk sac of the human embryo, and mainly in the red bone marrow after birth
Hematopoietic progenitor cells (committed stem cells)
Morphological changes during blood cell generation
1) The cell body changes from large to small, but the megakaryocyte changes from small to large.
2) The nucleus changes from large to small, but the megakaryocyte changes from small to large. Euchromatin changes from more to less, nuclei change from shallow to dark, and nucleoli change from obvious to missing.
3) The cytoplasm changes from less to more, and the basophilia gradually becomes weaker (lymphocytes and monocytes are still basophilic). The number of special structures has increased
4) Cell division ability changes from existence to non-existence (lymphocytes still have the potential to divide)
Cells containing azurophilic granules include neutrophils, lymphocytes, and monocytes
Reticulocytes and red blood cells have no nuclei
Hematopoietic tissue is composed of reticular tissue, hematopoietic cells and stromal cells
Macrophages (connective tissue), osteoclasts (bone tissue)
Contrast mast cells (loose connective tissue)
Blood
Serum: does not contain fibrinogen and large plasma proteins