Round, the nucleus is large and round, the nucleolus is obvious, and the cytoplasm is eosinophilic.

Prolonged arrest in the prophase of the first meiotic division

Cells are small and flat

From flat to cubic/cylindrical

From single layer to multi-layer

Located between the oocyte and the innermost follicle cell, they secrete together to form a thick eosinophilic membrane rich in glycoproteins.

zona pellucida protein ZP

As the size of primary follicles increases, spindle cells in the matrix surrounding the follicles proliferate and differentiate, gradually forming

Fluid cavities of varying sizes appear between the follicle cells and gradually merge into a large cavity, called the follicular cavity, which is filled with follicular fluid.

A layer of columnar follicle cells next to the zona pellucida, arranged radially

As the follicle cavity continues to expand, the primary oocyte, zona pellucida, corona radiata and surrounding follicle cells gradually reside on one side of the follicle cavity and protrude into the follicle cavity, which is called cumulus.

Follicle cells in the granulosa layer are called granulosa cells

The follicle cells surrounding the follicle cavity constitute the follicle wall. The follicle cells here are smaller in size and densely arranged in a granular shape, which is called the granulosa layer.

intima layer

Adventitia

The secondary oocyte continues to complete the second meiotic division to produce an egg cell and a second polar body.

degradation absorbed

There are many lipid droplets in the cytoplasm, which are light in color and large in number. They are located in the center of the corpus luteum.

Function

Deep staining, small amount, located around the corpus luteum

Function

In the early stage of hyperplasia, the uterine glands are short, straight and thin.

At the end of hyperplasia, the long curve of the uterine gland begins to secrete, and the spiral artery becomes long and curved.

On the 14th, one follicle matures and ovulates

The endometrium continues to proliferate and thicken

The uterine glands are longer and more curved, and the spiral arteries are longer and curved.

Predecidual cells (intracellular glycogen lipid droplets) (become decidual cells during pregnancy)

If there is no pregnancy, the functional layer of the endometrium will fall off and turn into menstrual period.